I was diagnosed with Autoimmune Hepatitis in November 2009 after a liver biopsy. I was put on 60mg prednisone and 50 mg of Imuran. Eventually my liver enzymes went down to normal and I remained at 50mg of Imuran and down to 5 mg of Prednisone. Then last September my liver enzymes went to ALT 284, then 650, then over 1,100. My AST was in 700's. It stayed there for a while, so the Dr. put me back on 60 mg prednisone. I stayed there and my liver levels have only gone down to the 300's ALT 200's AST. I am now on Endocort, 12 mg/day, 150 mg/day of Imuran and NO changes in my liver enzymes. I am sick all the time, tired all the time, fatigued, and nothing seems to be working. Any suggestions?? I went to a specialist who changed my meds to Endocort, but he doesn't have any further treatments in our plan. Any suggestions would be appreciated....