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Acute V/S Chronic hepatitis b serology.
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Acute V/S Chronic hepatitis b serology.

Hello to all so now i am going to explain about serology result.

Acute Hbv.
Hbsag+
anti-Hbc+
antiHbcIgM*+
Hbv Dna+
Hbeag+

Chronic hbv.
Hbsag+
anti-Hbc+
anti-hbc IgM-
Hbeag+-
Hbv Dna detecheble

in acute hepb the anti Hbc IgM always positive.
In chronic hepb IgG positive
3 Comments Post a Comment
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Avatar_dr_f_tn
Hi and thanks for sharing. An addition, duration is needed to diagnose a Chronic hepatitis B, which is a spectrum of disease usually characterised by the presence of detectable hepatitis B surface antigen (HBsAg) in the blood or serum for longer than six months. Those who are HBsAg-positive and HBeAg-negative (usually anti-HBe-positive) are infectious but generally of lower infectivity. Regards.
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Avatar_f_tn
Thanks dear anitha..
Is possible that antihbc igm decline fast such as
(value 0.05 method cmia) after 9 month of exposure because i had contracted with hbv on april 2013 and jan 2014 the igm show this 0.05 value.

Its possible plzzz help me
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Avatar_dr_f_tn
Hi, IgM is produced in the acute phase and IgG in the chronic phase. If HepB Core IgG Antibody is reactive, than you are in a chronic state or you had an infection in the past, which was resolved by your immune system. If HepB Core IgM Antibody is reactive, than you are in an acute state, which is an 95% chance to be cured (IgG must be nonreactive, otherwise you are in chronic active phase). Hope this helped and take care. Regards.
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