The Below Originally came from somewhere on medhelp, (I think it was in the ask a Dr Section)but when I originally put it in notepad, I didn't keep the link! So I didn't write this!
I'm sure some of the more informative ones will check in in the morning & can help you further! In The meantime I hope this helps some!
People make antibodies to hepatitis B if they are exposed to this virus and they can make different antibodies to different parts of the virus depending upon their immune systems. Almost everyone who is exposed to hepatitis B makes antibodies to the core part of the hepatitis B virus and we call this HbcAb or anti-HBc.
Things can get a little more complicated from here. Humans make two types of antibodies when they are exposed to a virus or bacteria. One is called the IgM antibody and the other is called the IgG antibody. When some one is exposed to a virus for the first time, they tend to make the IgM type antibody. About a month after the exposure, they make a second wave of antibody called the IgG. The IgG antibody tends to be more specific and powerful and it is the antibody that sticks around and gives extended or life-long immunity.
So anyone who is exposed to hepatitis B will have "anti-HBc" antibody, but many people feel that anti-HBc IgM is good test for a recent hepatitis B infection or exposure. The only problem, however, is that some individuals with hepatitis B can maintain high levels of anti-HBc for an extended period of time. In addition, some people who have had hepatitis B for years can go through periods where the hepatitis B acts up a little. We sometimes call this "reactivation". During these periods of reactivation, high levels of anti-HBc can become present again.
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