Female, 28 y.o.
I have a chronic Hepatitis B and have been taking Entecavir for 1 year and 3 month. I got pregnant 3 weeks ago while taking Entecavir (0.5mg daily). How Entecavir effects embroins during the pregnancy? Should i keep a baby?
My blood results now: ALT 15.0, AST 26.0.
I think you should keep the baby, and in my opinion, there is no compelling reason why you should not. I am not a doctor and I know a mother has different perspective on any kind of treatment during pregnancy.I copy an extract from a recent article:
"Safety data on HBV antivirals during pregnancy come from two major sources, the antiretroviral pregnancy registry (APR)  and the Development of AntiRetroviral Therapy Study (DART) . There was no significant difference in the rate of adverse outcomes reported if an HBV antiviral drug was initially used in the first trimester (3.0 and 2.1%) compared to the second or third trimester (2.5 and 2.1%) of pregnancy. These rates compare favourably to the background 2.72% rate of defects in the general population reported by the CDC birth defect "
The whole article is available at:
I suggest you talk to your liver specialist and gynaecologist about any concerns you may have.
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