I am on entecavir, HBV dna und at 4 weeks after starting the treatment. Now my doctor is suggesting HBV dna and Liver panel at every 3 months and AFP and ultra sound at 6 months interval. Considering that qHbsag and fibroscan are not available in USA, this plan seems reasonable to me. Any suggestions?
without fibroscan and hbsag quant is like a blind driving a car if there was liver damage......in any case unless you are hbeag pos entecavir will make no difference to hbsag
as regards fibroscan: did you have biopsy before taking etv?what was liver damage?as you may easily understand fibroscan is not available to just get all on therapy since you can t really see when the liver gets damaged and start therapy only then.
if you have cheap flights like in europe (as expensive as a bus/taxi) i d move to have fibroscan and hbsag somewhere else
if you are hbvdna und at 4 weeks no need to check before 6 months unless cirrhosis is present
well liver has no damage and biopsy was probably wrong with f3, anyway fibroscan less than 7kpa is not relevant damage and less than 8kpa reduced hcc risk so it was possible for you to just monitor
anyway now better stay with etv 1-3 years and then add on intf if no new drugs available
monitor hbsag quant because it can rise instead of go down on antivirals, when it reaches a low value intf add on can be tried.on the trials there was a patient with hbsag 8000iu/ml at 3 years of etv therapy, then intf was added and hbsag got to about 100iu/ml in 48weeks
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