I wouldn't use it. Sadly it may take another 5-10 years before there is a cure.
No, Hbv isn't a "harmless" disease and the antivirals we use has caused me more side effects than anything. When you've known or had a friend die of Hbv I wouldn't say it's "harmless".
This seems really dangerous. Beta cells, podocytes.. Scary
thanx friends for ur helpful replies. steff u r right justifying virus as harmless and study for hope is very correct on effect on mouse and human can be different since hbv is a human virus. Thanx stephen for eye opening. The Wait continues.
ph5??? that ain't too acidic?? anyways pal thanx for ur prestigious replies.
I too was very excited when the press release first came out, reinforced by the fact it was from a very prestigious Australian institute. It was news repeated all over the Internet for days. With rapid advance into a phase 2 clinical trial, again in Australia, our hopes were all raised. Then came the suspension of the trial, followed by deafening silence. I wrote to the public relation dept of WEHI, he washed his hands over the whole affair and passed responsibility to Tetralogic, even though their chief investigator was an advisor to Testralogic, the same one who flowed the idea that there will be a new clinical trial in India, in July 2016.
I learned a painful lesson and is now more cynical.
Birinapant cannot meaningfully used orally, there is almost no absorption from the gi tract. It has to be infused over 30 minutes from a solution of pH 5, 50ml approximately, in 50 millimolar of sodium citrate once weekly at a dose of no more than 15mg per square meter. This is the way it is used in the cancer trials.
you can easily end up dead with this vs an hameless virus like hbv.dont waste your time or life for nothing
There is absolutely no proof that Birinapant will cure HBV. Don't believe in the hype expressed in press release from Walter Eliza Hall, the institute where the scientists work.