CHRONIC HEPATITIS

WHAT IS THE SIGNIFICANCE OF AFTER 6 MONTHS OF ACUTE HEP B HAVING THE SURFACE AND E ANTIGENS AND ANTIBODIES ALL POSITIVE??  IS THIS CHRONIC? DOES IT REQUIRE TREATMENT.
ANNIE930

[stef2011]

no idea but it is cronic (chronic) if you are over 6 months, maximum time to see clearance can also be one year but this in normal cases

treatment is required only if you have hbvdna>2000iu/ml, alt>19, liver damage>f2

i'd find a good liver specialist and a biopsy to see what's happening in the liver.what happens in the blood is not the same as in the liver but on normal cases blood reflects liver in a certain way

[stef2011]

found article about hbe pos hbeab pos:
http://www.hbvadvocate.org/news/HBJ7.8.htm

Concurrent “e” Antigen and Antibody Can Indicate High Risk of Liver Damage
Some patients with chronic hepatitis B test positive for the hepatitis B “e” antigen (HBeAg) and the “e” antibody simultaneously in the same lab test. Chinese researchers closely monitored 169 patients who had both the “e” antigen and antibody to see what the concurrent “e” antigen and antibody status had on their health.

Writing in the July 2010 issue of the Journal of Viral Hepatology, researchers reported that the dual appearance of “e” antigen and antibody occurred most frequently in patients of medium age who had elevated viral load (HBV DNA in their bloodstream) and above-normal alanine aminotransferase (ALT) levels, which increase when liver cells are damaged or die.

The viral load and liver damage were more pronounced than in comparison patients who had either the “e” antibody or the “e” antigen.

In patients who had never been treated with an antiviral, concurrent “e” antigen and antibody status tended to indicate the presence of liver disease, researchers concluded.