Hepatitis B Community
CMIA or ELISA
About This Community:

This forum is an un-mediated, patient-to-patient forum for questions and support regarding Hepatitis B. Topics in this forum include but are not limited to, Causes, Diagnosis, Family and Relationships, Living With Hepatitis B, Research Updates, Treatment, Success Stories, Support, Symptoms.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

CMIA or ELISA

During a blood test I noticed that I have elevated liver enzyme levels

S.G.O.T 62 u/l
S.G.P.T 216 u/l
Total Bilirubin 3.07 mg/dl

I took a hepatitis profile test and got the following for Hepatitis B.

HBs Ag (CMIA, Australia Antigen) - Negative
Anti HB c IgM (CLIA) - Negative
Anti HB c Total (CLIA) - Negative
HBe Ag (CLIA) - Negative
Anti HBe (CLIA) - Negative
Anti HBs (CLIA), (quantitative) : 1.45 IU / L

After showing all thees reports to a senior doctor I was seeing, she said that I need to take the following tests

HBS-AG (ELISA)
HCV (ELISA)

since ELISA is more reliable.

Is that true ? Is ELISA more reliable than CMIA, what about the false negatives in CMIA?

Please help
8 Comments Post a Comment
Blank
Avatar_m_tn
Is that true ? Is ELISA more reliable than CMIA, what about the false negatives in CMIA?

it is machine used that matters and best machines are architect or elecsys with kits for automated hbsag quantitative in iu/ml
Blank
Avatar_m_tn
I don't think you have Hepatitis B, since both your HBsAg and HBcAb are negative. Have you been vaccinated against HBV? This will explain the presence of HBsAb. However your ALT (SGPT) is elevated and this should be investigated - drinking, fatty liver, medication? A HCV test is reasonable.
Blank
Avatar_m_tn
stef2011

Thank you for your response!.

The test mentioned ABBOT Architect is it the same 'architect' you are mentioning here ?
Blank
Avatar_m_tn
Thank you for your repsonse!

I took a HCV test (CMIA - abbott architect) it was negative!.
Blank
Avatar_m_tn
Anti HBs (CLIA), (quantitative) : 1.45 IU / L

I didn't mention the biological reference levels

10 IU / L  - Acquired Immunity.

Yes I was on antibiotics medication in the last month, and my SGPT levels were high and it became low, and it started rising up again.
Blank
Avatar_m_tn
didnt read all your markers, i also think it is not hbv

check also HEV and HAV

ast and alt can rise because of antibiotics, they are very toxic to liver and kidneys.i also got creatinine clearance (kidneys function) below normal due to an antibiotic
Blank
Avatar_m_tn
Thanks for you response! I'll update this post after I am done with the test!
Blank
Avatar_m_tn
Thanks stef2011 and StephenCastleCrag for your amazing work here.
The ELISA tests for B and C turned out negative.
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis B Community Resources
RSS Expert Activity
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
Top Hepatitis Answerers
Avatar_m_tn
Blank
stef2011
Italy
Avatar_m_tn
Blank
StephenCastlecrag
Australia
Avatar_m_tn
Blank
SafiSifa
Izmir, Turkey
7951432_tn?1424719262
Blank
flyinsky
paris, France
Avatar_m_tn
Blank
mike9111
MI
Avatar_f_tn
Blank
Ibro982003