Do I need medication besides regular checkup?

[Mrshappy]

I am 36 this year. I have been tested as HepB carrier since 2004. Regular tests shows no problem with liver but AST has been slightly high and DNA result shows the virus very active. Doctor said as virus is active,I am 10 times more chances develop to cancer than normal HepB patience, she recommended me to participate in hospital new medication trial. Do I need immediate treatment?
Here is my recent test result, others are ok except for these:
- AST is 53
- HBeAg is Reactive
DNA test:
- HBV viral load 3.33x10 8 copies/ml(8.52 LOG)
4.5x10 7 IU/ml (7.65 LOG)
- HBVP comment : lower detection limit for HBV real_time PCR 100 copiers/ml(2.0LOG) or 13.5IU/ml(1.13LOG)

[cajim]

Help:  whole grain food, yam, potato, corn, vitamins from vegetables and fruits, proteins from potable water fish and beef.

Avoid:  spicy foods, fried foods, cholocates, high starch high fat foods, greesy foods, alcohol, etc.

[Mrshappy]

Is there any food or medication will help to strength the immune system ? and at the same time to avoid certain food.

[cajim]

Looks at you are at immune-tolerant phase.

From 2007 Guideline:

Among individuals with perinatally acquired HBV infection, a large percent of HBeAg-positive patients have high serum HBV DNA but normal ALT levels.  These patients are considered to be in the “immune tolerant” phase.  Many of these patients develop HBeAg-positive chronic hepatitis B with elevated ALT levels in later life.  In sub-Saharan Africa, Alaska, and Mediterranean countries, transmission of HBV usually occurs from person to person during childhood.  In these populations most children who are HBeAg positive have elevated ALT levels and seroconversion to anti-HBe is common near or shortly after the onset of puberty.  In developed countries, HBV infection is usually acquired during adulthood through sexual transmission and injecting drug use.  Very little longitudinal data are available, but liver disease is generally present in persons with high HBV DNA levels.  Among carriers with elevated ALT levels, the rate of clearance of HBeAg averages between 8% and 12% per year but is much lower in carriers who are in the immune tolerant phase (mostly Asian children and young adults with normal ALT levels) and in immunocompromised subjects.  HBeAg clearance may follow an exacerbation of hepatitis, manifested by an elevation of ALT levels.  Older age, higher ALT, and HBV genotype B (vs. C) are associated with higher rates of spontaneous HBeAg clearance.

Follow-up of Patients Not Initially Considered for Treatment:

HBeAg-Positive Patients with High Serum HBV DNA but Normal ALT Levels. These patients should be monitored at 3 to 6 month intervals.  More frequent monitoring should be performed when ALT levels become elevated.  Patients who remain HBeAg positive with HBV DNA levels greater than 20,000 IU/ml after a 3 to 6 month period of elevated ALT levels greater than two times the upper limit of normal should be considered for liver biopsy and antiviral treatment.  Liver biopsy and treatment should also be considered in patients with persistent borderline normal or slightly elevated ALT levels particularly if the patient is above the age of 40.  Liver biopsy is usually not necessary in young patients (below 30) who are HBeAg-positive and have persistently normal ALT.