Do I need treatment for this level of DNA results?

[domoreforless]

I have been a carrier since I was 5 when I was injected with Hep-B virus blood into my body.  Now I am 30.  No family members have been infected from me.

I recently had the test showing Hep B Antigen negative, Hep B Antibody positive.

But what has me worried is the DNA results.  9400 H IU/ML and 54700 H copies/ml.

Do i need treatment for this level of DNA results?

Thanks in advance for your time.

[domoreforless]

Thanks so much for the detailed reply. I live in big cities in the US, will definitely take more recommended tests.......

Will keep you posted.......God bless you.

[stef2011]

first of all hbvdna has no meaning for infection or liver damage, so just a test of hbvdna is useless.the main use of this test is to become undetactable in case of antiviral treatement because detactable hbvdna can made virus mutations and in case of liver damage because no hbvdna detactable is equal to no or almost no liver damage

Hep B Antigen negative, Hep B Antibody positive.
which antigen, there are many many antigens and only hbsag antigene is important.but i guess you are talking about hbeag correct?
if so hbeag has become negative and hbeab positive, this is bad if you plan therapy to eradicate virus because hbeag pos have more chances to get rid of hbv

But what has me worried is the DNA results.  9400 H IU/ML and 54700 H copies/ml.
as said above no meaning

Do i need treatment for this level of DNA results?
as said above hbvdna has no meaning

what you have to do for most updated monitoring of hbv, unless you live in undevelopped countries or US,UK, canada which are like undevelopped countries for hbv and have no fibroscan and no hbsag quant available (probably marketing reasons so you can t monitor properly and are easily pushed to take antivirals even when useless)

most important and only test to monitor liver damage and fibrosis:
fibroscan every 6 months

most important to save your life in case liver cancer develops, this doesn t detect liver damage at all, if it does it is too advanced and not possible to regress damage:
ultrasound every 6 months + afp blood test

important to see when it is the best moment to start a thrapy and try to get rid of hbv:
hbsag quantification in iu/ml, only abbott architect and roches quant (and a few others) can make hbsag quantification in iu/ml:
when hbsag is ess than 1500iu/ml immune modulators have a high chance of eradicating hbv.for higher values very very difficult (immune modulators interferon, alinia)
hbsag level reflects number of infected cells in the liver (cccdna) and immune system strenght and activation (only imune system ad immne modulators lower this)

hbvdna
just to see how it flactuates but not really important when you monitor by fibroscan and US, plus hbsag and alt/ast

alt/ast
they can tell you about liver damage when you have the test but not accumulated damage, when you have fibroscan plus alt/ast you might have a better picture of the disease

hbcab igm quantification
when higher than 0,2s/co means immune activation, this usually happens with alt flares and hbcab igm>0.2s/co, alt flare, decreasing hbvdna and hbsag can signal the best moment to start an immune modulator since there is an active immune response and try to eradicate virus

use of antivirals like tenofovir or entecavir with no liver damage is almost useless when you monitor like i said above
these are hbv guidelines (except they tend to give antivirals in US for any hbvdna quant but that's marketing, not scientific).in europe and italy all above is monitored and if no liver damage there is a tendency not to use antivirals
it may be good to use antivirals after 35-40yo since rsk for liver cancer and cirrhosis becomes higher but if you monitor so closely by fibroscan and US you are safe and know when you need to block hbvdna

hbvdna is not the virus, is not virions, is just virus replication and when undetactable in blood is just lowered replication.it has nothing to do with infection and infection can spread to more liver cells even if hbvdna is und