What should be recommended as first line therapy for HBV ? Truvada or baraclude?
tenofovir (not truvada)
peginterferon which will be changed with new interferon lambda which doesn t have all severe sides normal interferon has
truvada is association of tenofovir+ftc, some more potency than tenofovir alone, some more sides on kidneys, more genetic barrier to resistance.i'd not use it if tenofovir fully suppress hbvdna since we haven t seen any resistance from tenofovir.
in a couple of years if not earlier we will have cmx157, new formula of tenofovir, no sides, 4.5 fold more potency, so i think truvada is ok only on resistant hbv strains, when tnf doesn t work
think truvada (tdf+ FTC) is a better choice since baraclude may develop resistance?
tenofovir is much better and little more potent than etv, but the good of etv is it has no sides at all, so every drug has its pros and cons.
for example this week i have tried tenofovir+etv+ntz, unfortunately not for me, creatinine jumped to 1.21 (still normal range) in 1 week, maybe i will try again after the use of some antioxidants that prevent kidneys damage
there is no clear data but one thin is certain it is better to use tnf without any resistance be baraclude or lam
how do I know if a person is in immune tolerant phase and doesn't need treatment?
hbvdna in the millions/billions, alt normal, hbsag very high log4-5 or more, fibroscan or biopsy with no fibrosis
Copyright 1994-2017MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.