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GCMAF therapy


first low dose 0.125ml, everything ok, i feel nothing unusual

headache or tireness are sometimes reported as the immune system activates at first injections but i felt nothing

134 Responses
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Avatar universal
Keeping all our fingers crossed for you :-)
Helpful - 1
Avatar universal
Dear Stef,                   I am HbsAg +ve donno since when. I got to know when i donated blood in 2011 december. Tested HBV DNA on Sep 2012 and it is 4540642IU/ml = 26426536 copies/ml, ALT - 66, AST - 48, rest all LFT is within normal range, i was feeling mild pain under the right lower ribs, HbeAg is Negative and Anti HbeAg is +ve. Doc advise to take tdf for six months and test again. 
Aug 2013 report is HBV DNA is < 6 iu/ ml = < 35 copies/ml. Alt 26 and Ast 26. Rest all reports are within normal. What is the next course of treatmant? Pls advise. I am feeling occassional mild pain under the right lower ribs.
Helpful - 0
Avatar universal

no it is a very complex test and only few research labs are doing the tests in europe also for private patients, ELN in holland is the only one i know or redlabs.com but also redlabs ships to ELN

nagalase i elevated on hbv too many members sent me test results and it is very elavated, all i received was from 3 to min 6.7 (autism, cfs have values like 1 or 1.5 only metastatic cancers have high values like 5 or 7), i received only one test from a member with hbsab between 10-30miu/ml and his nagalase was almost normal around 0.69

so in the end the experience with gcmaf and hbv is as regards my case:
fast cirrhosis regression (probably the effect of gcmaf plus heptech), latest research has shown stemcell activation

no effect on hbv infection but i never checked if i reached normal nagalase because it was too heavy to travel to holland, my last test was nagalase around 2
now we have labs in italy shipping the nagalase test to holland so i will recheck it soon
Helpful - 0
Avatar universal
stef, is there other indirect test available to check the neglase level indirectly which is easily available.
Helpful - 0
Avatar universal
What about doing high doses of intravenous vitamin C to help stimulate the immune system?

I think you are right on the nagalase levels relating to macrophage suppression. I suspect that is why all of the important vitamins with us are low..  
Helpful - 0
Avatar universal
There's also a lab in Australia, called:

integrative laboratory services, 1046A Dandenong Road Carnegie, Victoria 3163.

Tel: (03) 95738888
Fax: (03) 9578899
Helpful - 0
Avatar universal

we all had that liver pain and it means nothing, fibroscan will confeirm if you need treatment or can wait for real hbv drugs that cure hbv, just keep monitoring especially hbsag quant in iu/ml, fibroscan and ast/alt
Helpful - 0
Avatar universal
must check HbsAG quantity and fibroscan inconjunction wtih hep DNA.  HEp DNA in itself cannot tell the whole story anymore.  
Helpful - 0
Avatar universal
Tenofovir or entecavir is fine. But know that it is lifetime in our cases with e negative hep b.

You can use regular interferon and do injections every day. It is even cheaper then tenofovir.
Helpful - 0
Avatar universal
Dear Stef
              I am HbsAg +ve donno since when. I got to know when i donated blood last year december. presently HBV DNA is 4540642IU/ml = 26426536 copies/ml, ALT - 66, AST - 48, rest all LFT is within normal range, i am feeling mild pain under the right lower ribs, HbeAg is Negative and Anti HbeAg is +ve. Please Advise. Doc is suggesting Interferon which i cannot afford due to its cost or tab Tenovir one each day. is it ok
Helpful - 0
Avatar universal

it can be many things, all that matters is:
serum calcium or unrine calcium normal
vitd25oh not more than 100ng/ml and not less 60ng/ml
Helpful - 0
Avatar universal
I started sweating at night since I  take 10.000 iu of vitamin d. Does that mean i have activated my immune system? I do feel more energy.
Helpful - 0
Avatar universal

depends person to person ad even vdr is not the key of gcmaf, the probiotic type works on all vdr types while the injectable does not work on one vdr type

anyway i dont think gcmaf can clear hbv, it has worked in cases of hbv acquired as adults with aids/immune suppression, gcmaf corrected immune suppression and hbv got cleared, in our cases of hbv infection from birth i dont think it works

vitd25oh levels work as antiviral when reaching 80-90ng/ml on some members here
Helpful - 0
Avatar universal
Thanks for sharing your experience and informing the other members!

Regarding the downregulated VDR, why would they put it on gcmaf's site, if this is disinformation? Did you talk to the persons selling you the gcmaf about this, asking them why do they put disinformation on their site?...it does not make much sense to me that those very smart people at gcmaf would put disinformation on their site, although it could happen.

Not to mention that M Marshall (the scientist who came up with the VDR theory) did this for years with public conferences and everything (check on youtube), this is not a single isolated study made in a bogus lab.

I am not saying you are wrong, my problem is the same as yours (chronic hep b) and I am trying to find a way out of this. You seem to be much more experienced/informed then me, but it does not make sense this whole VDR receptor theory is misinformation. Did you, at least, checked your 1,25-d level also?

I know vit D increases immune function and everything, but the right approach is:
1) to supplement it
2) to detox the VDR receptor (downregulated by certains pathogens, according to dr Marshall) so the D level increases by itself to normal?

I guess it depends from person to person. Some will have VDR blocked, some will just need more sun.

Also, there is something called Vit D co-factors, for example: http://www.freegrab.net/cofactors1.htm, but many other info about it all over the net.
Helpful - 0
Avatar universal
Since you recommended 10,000iu of vitamin D3..  my chest pains have gone. I don't need to take aspirin anymore. And my energy levels are up.

You don't know if anybody in the US sells/makes gcmaf?  

The key is the  immune system no doubt to overcome HBV..
Helpful - 0
Avatar universal

still taking d3 10.000iu to keep optimum ranges, vit d has no immuen suppression at all, it is all disinformation, vit d increases immune function ,trl7 receptors and has antiviral effect on hbv and hcv well known and studied

i am using probiotic gcmaf and not the injectable, while on imiquimod i tried to stop gcmaf 1 week and i felt all imiquimod sides due to interferon production so started back again.without gcmaf i could not eat, severe pains all over body and more fever

on cancer gcmaf has made chemio sides to zero on many patient, i have experinced a similar effect with imiquimod interferon sides
Helpful - 0
Avatar universal
You are still doing it, any updates?

Also, on gcMAF's site at the "Latest Links" there is the VDR receptor theory saying high dose Vit D could do you more harm then good in the long run (suppresses the immune system), be careful with that. Should test both D 25 and 1,25-D according to that site.
Helpful - 0
1435203 tn?1307111807
good luck hope this is the answer to our prayers.
Helpful - 0
Avatar universal

hbsag, alt early next week

fibro, vit d end of may

Helpful - 0
Avatar universal
Any update (ALT, HbsAg, Fibroscan, Vit D) Stef?
Helpful - 0
Avatar universal

update of feb 7th 2012 tests, hbsag still going down

Hbsag
4201iu/ml    feb 2012
4572iu/ml    december 2011
5236,59iu/ml
4995iu/ml
5484iu/ml
started gcmaf
6255iu/ml
5381iu/ml
6217,9iu/ml
4590iu/ml
7272iu/ml
5397iu/ml
4873,8iu/ml (4months on entecavir already)

ALT
41   feb  2012
54   jan 2012
43   dec 2011
37   oct  2011
Helpful - 0
Avatar universal

anyway we do know why hbv gets cronic, hbsag depress immune system and has receptors for both macrophages and dentric cells making them non reactive to the virus

the key is get macrophages and dentric cells to uptake hbsag and start an immune response to the virus or block hbsag like drugs on human trials since many years.proble is drug makers are not interested to market this fast cure discovered from a small pharma called replicor

anyway i ll continue gcmaf to get my nagalase to normal, and in may i will add interferon to antivirals, response to this combo is 90% with clearance in 40% at 1 year and the rest still clearing in the second year
Helpful - 0
Avatar universal

nothing, i am the only one trying gcmaf with hbv, the same one in the cfs forum

there is another italian guy who took gcmaf for 24 weeks but he had hiv+hbv coinfection and was infected as an adult even if immune systm can be damaged it is not possible to say gcmaf cleared his hbv.
anyway his experience is 6months of hbv infection and after gcmaf he cleared  hbv almost immediately.he had poor tests so we cannot say

hiv, after 24 weeks on gcmaf he stopped hiv drugs and hivrna stayed und but he stopped gcmaf and never had tests like nagalase or expert doctors to monitor, in his area hospitals are very very poor quality and we often hear of people dye from bad healthcare.so no conclusions can be obtained from this single case
Helpful - 0
Avatar universal
Thank you for your answere. I thought I ask it here because hbv-people are more in to the liver. The digital explanation is clear. I now need to find an other reason why my meds work different.

My nagalase went down on Gc Maf and as I've heard this happens in 80 % of cfs. I have had 18 injections and it went down from 2,4 to 0,6. Most cfs have initial nagalase between 2 and 4 and this level is not related to severity of the sickness.

I am a high responder and my nagalase went down very fast compared to others who might need between 20 and 50 injections to get within reference range.

Now my body is detoxing a lot. My c4a was very high after my last injection which is a sign something is being fought.
I am now 16 weeks further but still very sick. I have a lot of problems with high histamin which gives me shortness of breath and other problems. My post-exercise recovery, which is the main problem in cfs, seems to be slightly improving though.

As Gc Maf is still very 'new' as a treatment it is interesting to read how it effects people with different diseases. A lot of cfs get a lot of inflammation and problems with histamin. On the cfs forum there is also a Hbv and there seems to be a lot of difference in reactions to the treatment. Also HIV and cancer react different. In cfs the main problem is we dont know what we are fighting as we dont know the cause of our disease. We only now of some co-infections and we have immune abnormalities. Cytokines improve on the treatment to normal levels though.

New results on treatment of cfs with Gc Maf are expected coming months. Are there resent publications on Gc in Hbv?

Thanks,
Spring

Helpful - 0
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