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Good news

Finally got my post interferon treatment result today seven months later.
Surface antigen and HBDNA all negative.
ALT normal.
E-antigen = negative
Antibody = positive
Surface antigen titre level = not available yet.... will report next week.
Good luck guys.
27 Comments Post a Comment
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Avatar_m_tn
congrats...

how was your results before treatment. Could you please share in detail?
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Avatar_m_tn
Wow! Looking forward to more detail. Congrats!
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Avatar_f_tn
Results and timelines:

Date             ALT
30-Oct-12      236
06-Nov-12     306
10-Dec-12     298
18-Jan-13     175
14-Feb-13     229
20-Mar-13      499
23-Apr-13      352
22-May-13     116
15/07/13         81
30/11/13         35
16/06/14         32


HBDNA
9/12/2011      73,729
26/4/2012      12,872
23/8/2012      57,800
30/10/12       292,034    Pre-treatment (Baseline)
10/12/12       30,992      
18/1/13        188,190    12 Weeks treatment--i suspect intf was off.
16/04/13      1400         24 Weeks
15/07/13      <20 iu/ml 36 weeks
14/10/13    <20 iu/ml 48 weeks
30/11/13     48 iu/ml 60 weeks – (end of treatment)
16/06/14      <20 iu/ml- (Post treatment)


Surface antigen
Baseline: 4959 IU/ml
9 months’ time point: 81 IU/ml
7 moths post treatment: undetected

HB genotype: B
E- Antigen status pre-treatment: Negative.
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Avatar_m_tn
Congrats. Really encouraging
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Avatar_m_tn
Fantastic!
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Avatar_m_tn
great news, did u receive any oral antiviral  before interferon
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Avatar_f_tn
No oral antivirus.
Interferon mono therapy.
Thanks
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Avatar_m_tn
well done! Congratulations! What about your anti-hbs titer? did you check?
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Avatar_f_tn
Result will be available next week. If the level is low, I plan to get vaccine to boast it. Currently working with one of the best guy in the field so we have discussed it.
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Avatar_m_tn
1. did u take any supplements in addition to the interferon
2. was it Alfa interferon 2a or 2b or peginterferon interferon
3. what time in the day were u taking the injection.
4. which site of your body were u injecting it.
sorry for all this questions I am also considering to go for Alfa interferon 2b treatment.
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Avatar_f_tn
1. did u take any supplements in addition to the interferon: vitamin do but don't believe it makes any different.
2. was it Alfa interferon 2a or 2b or peginterferon interferon : Peg. In tf.
3. what time in the day were u taking the injection. :Evening, near to bedtime.
4. which site of your body were u injecting it. : shoulder.
sorry for all this questions I am also considering to go for Alfa interferon 2b treatment.

Hope this helps.
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Avatar_m_tn
thanks for that, hope your hbsab level will be high.
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Avatar_m_tn
Beautiful result. Many congrats!!
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Avatar_f_tn
Good luck to all of you guys and I hope that you ll tell your stories soon. I plan to document my treatment experience and possibly publish it soon. I will also post my anti body titre level next week when the result becomes ready.
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Avatar_m_tn
Amen, but were u taking vitamin d
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Avatar_f_tn
I did take vitamin D for a limited time.
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Avatar_m_tn
thanks hbv is such that u take so many things without fingering which make an impact.
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Avatar_m_tn
Vit D3 should be taken regardless of HBV infection or not. It might be impacted as the stronger the immune system pre-IFN, the better chances IFN will work with your stronger immune and knocked HBV down.

Your ALT level definitely give it a kicked Mrt. Mine was a high of 225. Last checked, still at 124.
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Avatar_f_tn
I agree that high ALT is a big factor and the reason behind the choice interferon.
I got a confirmatory result today which confirmed surface and e antigen negative. Alt is 40 and antibody less 10iu/ml. Will test I'm few months and decide if a boast is required to increase the titre.
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Avatar_m_tn
you re still in the fight then, keep healthy lifestyle and good rest

vitamin d is a must both now and in the case of boosting by hbv vaccine, antibodies titers to vaccines are higher in those getting vit d supplementation
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Avatar_m_tn
vitamin d is a must both now and in the case of boosting by hbv vaccine, antibodies titers to vaccines are higher in those getting vit d supplementation, although response or no response does not change
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Avatar_f_tn
I got one year post intf test today and still maintained negative surface antigen and hbdna.  All other liver panel indicators are good except that the antibody titre is still less than 10iu.
Good luck guys.
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Avatar_m_tn
Since your antibody titre have not increased yet, have you tried then vaccine?
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Avatar_m_tn
Do you gain weight after stopping interferon?
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Avatar_f_tn
I have added weight but trying to control it. I lost about 10kg during the treatment which lasted for 15 months but quickly gained the Weight back and added additional 5kg. Do you have weight issue after interferon treatment? @ErichH I will explore the option of vaccine and will discuss it with the consultant.
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Avatar_m_tn
I am now under interferon, also lost around 10kg during the treatment and wanted to check with you what to expect after interferon stopped.
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Avatar_f_tn
You will gain the weight back as soon as you completed the treatment. Good luck and all the best.
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