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Green tea for HBV
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Green tea for HBV

The green tea polyphenol, epigallocatechin-3-gallate, possesses the antiviral activity necessary to fight against the hepatitis B virus replication in vitro

Jing-yao PANG, Kui-jun ZHAO, Jia-bo WANG, Zhi-jie MA, Xiao-he XIAO

Beijing Friendship Hospital, Capital Medical University, Beijing, China; China Military Institute of Chinese Medicine, 302 Military Hospital, Beijing, China; Integrative Medicine Center, 302 Military Hospital, Beijing, China


Abstract: Although several antiviral drugs and vaccines are available for use against hepatitis B virus (HBV), hepatitis caused by HBV remains a major public health problem worldwide that has not yet been resolved, and new anti-HBV drugs are in great demand. The present study was performed to investigate the anti-HBV activity of epigallocatechin-3-gallate (EGCG), a natural-origin compound, in HepG2 2.2.15 cells. The antiviral activity of EGCG was examined by detecting the levels of HBsAg and HBeAg in the supernatant and extracellular HBV DNA. EGCG effectively suppressed the secretion of HBsAg and HBeAg from HepG2 2.2.15 cells in a dose- and time-dependent manner, and it showed stronger effects at the level of 0.11-0.44 μmol/ml (50-200 μg/ml) than lamivudine (3TC) at 0.87 μmol/ml (200μg/ml). EGCG also suppressed the amount of extracellular HBV DNA. The data indicated that EGCG possessed anti-HBV activity and suggested the potential of EGCG as an effective anti-HBV agent with low toxicity.

Link : http://www.zju.edu.cn/jzus/iparticle.php?doi=10.1631/jzus.B1300307

PDF file is available for download
2 Comments Post a Comment
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Avatar_m_tn
it does nothing in vivo as 99% of all studies in vitro, i drank it for years in my life, maybe it had little antioxidant effect
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Avatar_m_tn
The amount you have to take for this to work you can not get simply by drinking it. You would need to take supplements (and they have to be the right supplements). At a minimum 800mg once daily would be required to even show. Drinking Tea or splitting 400mg twice daily won't do anything.
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