Aa
HBV DNA Negative HbsAg positive
Dear Dr,
I was detected positive for Hepatits B around a year back. I do not know when I got infected.
My recent tests said
HbsAg +ve (obviously)
HbeAg -ve
HbeAb +ve
Negative for HIV , Hep C and Hep A
ALT - 54 (slightly above normal)
AST - 42 (slightly above normal)
HBV DNA PCR - negative
HBV Quantitative PCR - less than detectable range.
The test results are the same from past one year.
I have not undergone any treatment as I had already seroconverted by the time it was known that I was a carrier.
My doctor who is a gastroentrologist said that I am a healthy carrier,
not infected by pre-core mutant.
The doctor said that I may live for another 20 years(I am 29 yrs of age).
After which my immunity may go down and the virus may become active again.
I do not have any family history of Liver diseases or cancer or diabetes.
My Question is
1)Am I going to live only for another 20 years given my present condition of a healthy carrier.
2)What are the chances that the virus will become active again i.e HbeAg positive and DNA positive? If so ususally at what age?
3)Is it possible for the virus to be passive for a lifetime once suppressed naturally without treatment?
4)Will I ever show negative for HbsAg?
5)Is it OK to have ALT and AST slightly above normal in the present condition or is there any other reason for it?
6)Are there any good treatments available in the near future other than interferon or adefovir ?
Sorry for a long letter.I hope U understand my concern and will reply back to all my questions.
Thanks a lot in advance.
I was detected positive for Hepatits B around a year back. I do not know when I got infected.
My recent tests said
HbsAg +ve (obviously)
HbeAg -ve
HbeAb +ve
Negative for HIV , Hep C and Hep A
ALT - 54 (slightly above normal)
AST - 42 (slightly above normal)
HBV DNA PCR - negative
HBV Quantitative PCR - less than detectable range.
The test results are the same from past one year.
I have not undergone any treatment as I had already seroconverted by the time it was known that I was a carrier.
My doctor who is a gastroentrologist said that I am a healthy carrier,
not infected by pre-core mutant.
The doctor said that I may live for another 20 years(I am 29 yrs of age).
After which my immunity may go down and the virus may become active again.
I do not have any family history of Liver diseases or cancer or diabetes.
My Question is
1)Am I going to live only for another 20 years given my present condition of a healthy carrier.
2)What are the chances that the virus will become active again i.e HbeAg positive and DNA positive? If so ususally at what age?
3)Is it possible for the virus to be passive for a lifetime once suppressed naturally without treatment?
4)Will I ever show negative for HbsAg?
5)Is it OK to have ALT and AST slightly above normal in the present condition or is there any other reason for it?
6)Are there any good treatments available in the near future other than interferon or adefovir ?
Sorry for a long letter.I hope U understand my concern and will reply back to all my questions.
Thanks a lot in advance.
I'm sorry, I do not know what answers you'll find here, as this is a patient to patient forum. Most of us have Hep C, but maybe the ones who have Hep B will be able to answer some of your questions if they stop by.
I am having that liver pain that we can't have, worse now than ever. Still only a 3 on a 1 to 10, but more often and longer. Is this something to worry about? When I had my PCR, they also did ultra-sound and blood test for cancer, and they looked good. Thanks, Joni
the gastroenterology section in Med Help has an MD answering questions for a fee. This forum is a patient to patient with no MDs monitoring the questions.
One thing I can tell you though, no one can predict if you will live another 20 yrs, whether you are healthy or not, the statement by your doc was an educated guess.
good luck to you
One thing I can tell you though, no one can predict if you will live another 20 yrs, whether you are healthy or not, the statement by your doc was an educated guess.
good luck to you
This is a hard one for me to answer. I have had sugical pain since transplantation that is very hard to distinguish from the "liver pain" that I had pre-transplant. I really don't know what to tell you on this issue. My best guess is if your scans look good and your blood work looks good then you're probably okay. I sure hope this resolves quickly and that you are able to relax and get on with your life. Keep us posted and good luck. Mike
1 year post-tx all clear. Doc said CURED, not remission,not probably gone , but CURED. He said if it comes back it will be because I got reinfected. Pretty encouraging words. Male, 57, 1a. Did 48 weeks Peg-Intron and ribavirin. Not all that much fun but not totally horrible either. Definately worth it. Thanks to all that were here for encouragement and support. Indiana----Since I live fairly close, if you see someone in your pasture tonight it will be me. I plan on tipping Bertha myself tonight. Thanks again toall
Dear Apple13,
I have learned many important and helpful info. from MedHelp about HBV and now I will try my best to answer your #2 question.
You are considered a non-replicator ("carrier") when your HBsAg is +, HBeAg is - and HB DNA is - (which is exactly your case). This is the exact words from the Doctors from MedHelp "Non-replicators SHOULD NOT BE AT RISK for progressive liver disease but are infectious and are at risk for hepa B related liver cancer. While it is possible for a non-replicator to convert to a replicator, we feel this is VERY UNUSUAL unless the individual is immuno-compromised (such as after a TRANSPLANT)". "All patients with hepa B and HBsAg positive have some POTENTIAL TO CLEAR THEIR INFECTION SPONTANEOULY OVER TIME". I hope the above info. answers some of your questions.
I have learned many important and helpful info. from MedHelp about HBV and now I will try my best to answer your #2 question.
You are considered a non-replicator ("carrier") when your HBsAg is +, HBeAg is - and HB DNA is - (which is exactly your case). This is the exact words from the Doctors from MedHelp "Non-replicators SHOULD NOT BE AT RISK for progressive liver disease but are infectious and are at risk for hepa B related liver cancer. While it is possible for a non-replicator to convert to a replicator, we feel this is VERY UNUSUAL unless the individual is immuno-compromised (such as after a TRANSPLANT)". "All patients with hepa B and HBsAg positive have some POTENTIAL TO CLEAR THEIR INFECTION SPONTANEOULY OVER TIME". I hope the above info. answers some of your questions.
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