HBV Mortality - French Research In 2001

[Ann8]

Mortality related to HCV and HBV infections was estimated in
France. METHODS: A random sample (n=999) of death certificates was obtained
from all death certificates listing HBV, HCV, hepatitis, liver disease,
possible complication of cirrhosis, bacterial infection, HIV, or
transplantation (n=65,000) in France in 2001. Physicians who reported the
deaths were sent a questionnaire to identify how many deaths were related to
HBV/HCV infection. Completed forms were independently analyzed by a panel of
hepatologists. Death rates were estimated according to national population
census data. RESULTS: Estimated annual number of deaths associated with HCV
and HBV infection was 3618 and 1507, respectively (6.1 and 2.5 deaths per
100,000 inhabitants, respectively). Estimated number of deaths attributable to
HCV or HBV infection was 2646 and 1327, respectively (4.5 and 2.2 deaths per
100,000 inhabitants, respectively). In the HCV infection group, 95 percent had
cirrhosis; 33 percent had hepatocellular carcinoma (HCC). In the HBV infection
group, 93 percent had cirrhosis; 35 percent had HCC. Eleven percent of deaths
occurred in patients with HIV coinfection. Deaths related to HBV or HCV
infection occurred at an earlier age in patients with a history of excessive
alcohol consumption. CONCLUSIONS: In France, 4000-5000 deaths related to HCV
and HBV infection occurred in 2001. Alcohol consumption and HIV infection were
important co-factors. These data emphasize the need for ongoing, efficient
public health programs that include screening, management, and counseling for
HCV- and HBV-infected individuals.

[stevenNYer]

The numbers are reassuring.  The odds are still good.