As I learned from this forum any one having HBsAg is in-fact an active carrier. But his/her infection may be low or high based on DNA viral load. If you have a low viral load it mean you are low infectious. Even when PCR does not detect DNA load virus itself is there in the body and is replicating but at a very low rate. (Please correct me if I am wrong)
I am also HBeAg negative and HBeAb positive. How you have requested these Genotype test and how much it cost. Can anybody go for this or one need a referral from liver specialist?
Genotype: it could influence a decision to start treating with peginterferon. A and B are relatively more easily brought under control than C and D. The genotype also gives an indication as to how severe the disease is going to be.
HBeAg -ve people typically would have low viral replication -- in many cases, low enough to require no further treatment. If the DNA VL is high for Ag -ve people, it means that they have active viral replication despite their Ag -ve. Hence the treatment.
In general Ag +ve people fare worse than Ag -ve people, but keep in mind that this *by itself* is not a criterion for a prognosis or for starting treatment.
Yeah man is very confuse i have seroconverted doc said hbs ab - , hbe ag - and hbe ab + , but stil i read that hbe ag - is harder to treat! Why they need treat if seroconverted? They do the treat to seroconvert so.......?fuuuuu
Hello. bram44,you've mentioned the genotyping test. My husband had a visit with his doctor yesterday(3 mos. after starting Viread therapy) and asked about it. His VL dropped from about 400 000 UL/ml to just 100 IU/mL. It would be ideal to do the test now,before he goes UND.But the doctor said that this test is only reserved for clinical patients and referral for it,here in Canada, is not jon a walk-in basis. He also added that there have been reported inaccuracies with these test results. I don't know. I'm sort of disappoited that he is not easily available here in Canada. Take care-April
can anybody help to explain?
I would like to get an information about my husband's hep B blood test results.
hep B core IgM (HBcIgM) - negative
hep B surface Ag (HBsAg) - positive **
HBsAg value - 6899.00 IU/ML
hep B surface Ab (HBsAb) - negative
hep B surface Ab value - >2.0 mIU/ML 0.0 - 10.0
hep B e antigen (HBeAg) - negative
hep B e antibody (HBeAb) - positive **
I would like to know, how to read this results and what exactly does it mean. Does he have an active infection and is he infectious to others?
He has the virus since a childhood, the doctors say there is no treatment at the moment to get rid of the virus. I am just curious if there is still active virus and if he is infectious to the public. Does it affect the IVF treatment for us - I have been vaccinated and I am immune against hep B virus.
Thank you very much Marianna.
I am on Viread for last 9 months. Started with viral load of 30000 IU/ml (90000 copies/ml), with eAg -ve and HBV genome type A.
Viral load became undetectable in next tests (which is after 1,3,6,9 months). I continued to take medicine and still the viral load is undetectable. AST/ALT readings are normal (mine are always in the normal, even with the viral load).
My doctor asked me to stop taking the medicine after 12 months of use and monitor the viral load every 2-3 months.
Thought this is something useful for all eAg-ve (and eAb+ve) patients.
HBsAg value - 6899.00 IU/ML, this value is too high for inactive carrier so he just have low replication
since he is hbe negative and hbeab positive he might start off label treatment with alinia which can lower hbsag to negative in 1-2 years. i have the combo with entecavir and the first 4 weeks of combo hbsag dropped from about 5000 to 2000iu/ml, in a couple of days i will have the 12 weeks result
alinia is the only therapy that can help your husband to make hbsag negative.in case he also has hbvdna >2000iu/ml and high alt he can make combo like me with the following from most potent to less:
interferon+alinia, tenofovir+alinia, entecavir+alinia
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