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HBsAg Reactive
Sir for a job medical in 2005 i found incidently that

HBsAg +  ,   LFTs normal ,  HBeAg  Negative and HBe antibody positive

i had no problems with my health and still i am fit but now again in 2011 for another job medical my labs are as under

HBsAg Positive ,  HBs Ab Negative , HBc Ab Positive , HBeAg Negative ,  HBe Ab Positive , LFTs Normal and
PCR for HBV DNA ( Quantitative ) Negative

Now this HBsAg positive status is becoming a problem for my job abroad ,  how can i get it negative .. i am ready to take any medicines .. how about getting vaccine... interferon ... just want to get rid of this HBsAg please help me please
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and also what is the role of vaccination as i have a very very low anti HBs titre .
can it be useful ???
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what about simvastatin vit d and alinia instead of peg interferon bec its a lot cheaper and oral and very few side effects

pegintf is the main effector, vit d and alinia are just of little help to intf response.you may consider normal intf not peg which is out of patent and generic

kindly also mention the duration of peg interferon
it can be from 24 weeks to 48weeks

the role of vaccination...
this is of help only when hbsag is negative if hbsab does not develop
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also gcmaf might be a try if intf is very very expensive, gcmaf is 660€ for 2 months therapy but there is no data at all if it can clear hbv
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this peg interferon dose is 180 mcg once weekly for 24 to 48 weeks for hep b

can you confirm it
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peg interferon alpha 2 a 180 mcg once weekly
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you may do this:
start vit d supplements 10.000iu daily in case of vit d deficnecy 10-20ng/ml (test serum vit d25oh), in case normal take 5000iu daily until serum levels are 60-90ng/ml

when vitd25oh is at least 50ng/ml start alinia taken with meals every 4-5hrs to a total of 2-3g daily (pills are 500mg).take probiotics or bifidus yogurt while on alinia.do this for 4 to 12 weeks

check hbsag if still detactable add on pegintf+alinia+vit d3

since those who took alinia had hbsag drop of 1500-3000iu/ml in the first months it may be possible you clear hbsag by alinia only

update community with results
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regarding interferon for hep b

is it   peg interferon alfa-2a   180 mcg once weekly

kindly confirm it as i am checking its price in my country
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several intf can be used alpha-2a the most used i guess
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anyway at 19iu/ml it can be possible alinia clears hbsag in weeks since all those who tried it had decrease in thousands
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yea sure i am really desperate to lose this HBsAg .  i ll start medications real soon .  just completing my home work before going to gastroenterologist .
an i ll keep on updating the community
you are doing a lot for the community . again thanks a lot
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Bro, plz help me. i wan to know which Lab in Pakistan can do HbsA Quant. Thanks a lot.
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its done at chightai lahore lab
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did not take any drugs and repeated the test after 3 months and found it to be 13.7 from 19
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Now its 13.7
any comments and suggestions
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my HBsAg quantitative report says
  cut off value 0.05 IU/ml
patient value 19 IU/ml 06 months ago
after 3 months 13.7
and now will get report in a few days
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Now its 16

So depressed
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Now its 16
feeling depressed
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Did you start medication? What's the lab report? No need to be depressed, you are still healthy.
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just took vit D and hoped
as could not get alinia in pakistan
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HBsAg Quantitative 19.3 then 13.4 and now 16
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Why don't you do the Pegasys, stef2011 said it can clear. Maybe you should search Otan, a user here and learn his experience.
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actually i have quite a tough job now a days and  
taking pegasys with a tough job is difficult

Now arranged alinia
I have started  Vit D Alinia and simvastatin combo
will continue with these and may add pegasys after 3-4 months
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If my HbsAg is as low as you, i will do whatever I can to get rid of this virus. Many people can't even bring down their HbsAg to your level.
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Same here. Ali2456, people dream of getting numbers like yours, if they are truly correct. When they get those numbers they have a good chance of clearing for life.

You have a good chance of clearing the virus which millions of people are stuck with for life. If you don't make the right choices and continue to explore other methods than the virus can get the upper hand and the advantage.

It can mutate and your numbers can get in the millions, this could lead to Cirrhosis and HCC (liver cancer). You can also be very infectious and put your family and friends at risk.

If I were you I would take a more responsible approach.
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dear
i am greatful for comments
What can i do in your opinion
Wt do u suggest
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Whats situation at your end
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With numbers as low as yours I would do the following.

1. Start with a full set of labs and tests from a very good doctor
2. Get a genotype test and under an expert doctor look to start interferon therapy, possibly with Alinia

You may have a very good chance of clearing the virus if you act quick and smart. The virus is very smart, if you waste time it might get out of control of your immune system.

Also keep in mind in Pakistan most doctors are terrible. Your results could even be wrong.
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Any update ali? Did you start with peginterferon?
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Dear,

Please let me know that, in specifically my case where Hbsag value is 4007, which i have tested in June 2012 and DNA was not scanned in test. could i get success in medical examination for Australia immigration, as they have even mentioned on their website that they does not treat HBV as treat to public but in some cases need undertaking.
Please provide your doctrine in this regards, since i have received my EOI(Expression of Interest)  and have a chance of one month for visa application, but i need to pay a visa fees in this regards, which is approx 3060 AUS $ and i don't want to loos it.

Please advice.......
  
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Going to repeat the HBsAg quantitative
Did not take any medicines
18 months ago was 19
an year ago was 13.4
6 months ago 16

Fingers crossed lets see whats the result now
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hbsag + since 2005
anti hbs -
hbeag -
anti hbe +
alt and ast normal
hbv dna less than 116 copies / ml ( undetectable )

HBsAg quantitaive from 19 to 13.4 then 16 and now 20.23 over last one year
No treatment taken

Now have started with
-PEG interferon 180 mcg once weekly
-Alinia 2gm daily in divided doses
-Vit D
-Simvastatin 20 mg daily
Today was the first day
will recheck HBsAg after 8 weeks

any suggestion ?
any hopes ?
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test hbsag after 4 weeks instead of 8 weeks, its not too costly.
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yea its not that expensive
is it expected to come down so early
can be discouraging
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but check hbsag and cbc and report, it will be useful to predict future response.
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hbsag + since 2005
anti hbs -
hbeag -
anti hbe +
alt and ast normal
hbv dna less than 116 copies / ml ( undetectable )

HBsAg quantitaive from 19 to 13.4 then 16 and now 20.23 over last one year
No treatment taken

Now have started with
-PEG interferon 180 mcg once weekly
-Alinia 2gm daily in divided doses
-Vit D
-Simvastatin 20 mg daily

tolerated the first inj well
and continuing with the rest of meds
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20.23, and the unit is iu/ml?

hbsag should go und by 24 weeks, add hbv vaccine when hbsag goes und
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yes the unit is iu/ml
is that the right strategy
what do u think
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thanks a lot
i was waiting for your reply since the time i had inj pegasys 3 days ago
first day was awful and now feeling almost normal
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anything else i can do
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stef ???
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if you have reached good blood levels of vit d like 40-60ng/ml you can go on with pegintf and see hbsag at 24 weeks
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got two inj
many still to go
its tough but managable
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hey
got the 5th inj pegasys 180 mic today
platelet 159000
WBC 3000
ALT 103

ALT had always been normal before that  
HBsAg quantitative 20.9 iu/ml before starting therapy
Also taking Vit D

What does that mean
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hey stephen also comment on my raised ALT
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Newtr kindly comment on my raised ALT
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I am hoping it is an indication that your immune system is clearing the virus. Stef2011 will be able to tell you more. Keeping my fingers crossed for you.
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yea must think positive to cope up side effects of pegasys
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Hi ali! What sides are you experiencing while on int?
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a lot of weakness
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what happened?
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