HBV-DNA level and BCP 1762T/G1764A mutation in liver tissue independently predict postoperative survival in hepatocellular carcinoma
In conclusion, the amount of HBV-DNA in liver tissue and the presence of the basal core promoter mutation were two independent predictors for postoperative survival in HCC. A short stretch pre-S deletion located between codons 107 – 141 was strongly associated with a poorer postoperative prognosis. (HEPATOLOGY 2010.)
i guess the lower the virus the better in anycase...since A1762T/G1764A BCP and G1896A are the majority of hbv cronic forms worldwide, in these cases (also mine) hbvdna und and very low intraepatic hbvdna is the best.
these mutants can be present also on hbe positive.
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