HIV PEP and HBV

[frightened_indv]

Hi,

I was prescribed 1 month of Truvada immediately after an incident. I started it promptly. I was detected HbsAg/ australia antigen positive 6 years ago. After several repeated tests, my viral load (HBV DNA) was undetectable and HBeAg was negative. Last one was 1.5 years ago.
I stupidly did not disclose this to the doctor that prescribed Truvada and now I am worried that this could cause the HBV to mutate and reappear. Could it happen? What should I do?

[Arivancouver]

Hi everyone

Sorry for my poor English

I recently find out I have hep b
I'm going to see specialist by dec 11 2015

I'm so scared if I have HIV
I did test was negative
But I need to do one more in 3 months

I had unprotected oral sex with a girl

And also protected sex with two other girl buy using condom

And I got chlymidia and herpes

Anyone knows if people have HIV and hep b can live long enough ?

Thanks

[sorte]

Modern hiv tests are almost 100% conclusive 4 weeks after exposure. Go to some hiv forum and everyone will confirm.

[Aduiski]

P.s.

To be more precise, the above sentence of mine:

"If docs recommended you to take PEP, then I would advise you to complete it, but off course it is your personal decision."

was supposed to mean:

"If docs recommended you to take PEP BASED ON THEIR ASSESSMENT OF HIV RISK, then I would advise you to complete it, but off course it is your personal decision."


Also, i just remembered that few of the HIV PEP guidelines I read, recommended a few-months follow up of Hep B positive individuals after the competition of PEP, just so as to be sure there is not Hep B flare. However, none of these guidelines mentioned anything about Hep B positive people not taking HIV PEP or similar....which is yet another clear indication that this Hep B flare is for most of Hep B positive people a non-significant event...otherwise the guidelines would be more cautious in prescribing HIV PEP for HEP B carriers, but they are not.

If I personally would get into another HIV risk situation...I would for sure take another PEP course....based on all consultation I did with a number of Hepatitis B and HIV experts.

[Aduiski]

Hi,

I was in a very similar situation like you, but i did disclose my Hep B + status and then started to worry about the same issue as you do now.

I consulted some of the leading experts in Australia and Germany on this issue: weather there is a chance for Hep B to be affected by 1-month of HIV PEP.  They all said that it is very unlikely that this short course of PEP will affect Hep B. What happens in some of the Hep B positive individuals is that after stopping HIV PEP, there comes to Hep B flare (ALT/AST gets very high) but this flare usually comes and goes.
Basically the conclusion was to go with HIV PEP (if PEP was really indicated - in my case docs said it wasn't needed but I still took it due to my HIV paranoia).
I tested ALT/AST 2 weeks after stopping PEP, and again 3 months after stopping it, and it was same as it was before - no flare. My HBV DNA was a bit higher than usual, but then again my HBV DNA did fluctuate a bit on last few tests.

If docs recommended you to take PEP, then I would advise you to complete it, but off course it is your personal decision. PEP nowadays will eliminate HIV in 99% of people in which HIV enters, but make sure to take it exactly as prescribed and for 28 days (get your multiple alarm watches to remind you so you don't skip a dose). In fact, in recent history (with newest medicines) in Sydney (gay capita of Australia) they hasn't been a single HIV positive case for all people who took PEP as prescribed. From everything i heard and read, I strongly believe it is 99.99% effective if taken within first 36 hours of possible infection.

[StephenCastlecrag]

I have no idea the answers to your questions. In my personal opinion, the matter may not be that serious. Truvada is an accepted treatment for Hepatitis B. So no harm there. I don't think its short use will cause mutation, based on the thinking that it takes a while for any mutation to take hold and become widespread throughout all the infected cells, and secondly low rate of replication = low rate of mutation. So I would just check your hbvdna and liver functions to see whether the situation has changed.