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Help me understand these results

by biobrain, Jul 06, 2009 10:19AM
Please help me understand these results? Am I acute or positive? is this active or not?

Hepatitis B surface antigen detected by EIA

Hepatitis B core igm not detetecd

Hepatitis B e antgen not detected

Hepatitis B e antibodies detected
Member Comments (11)

by apache1, Jul 06, 2009 11:22AM
Well, with  +surface antigens, looks like you have HBV

Check out the diagnostic matrix on our welcome page , it might help you figure this out.
http://www.medhelp.org/health_pages/Hepatitis/HepB-Introduction--Welcome-Page/show/34?cid=153

also
http://www.vaccinationnews.com/DailyNews/March2002/HowInterpretHepBPanelResults.htm

hope this helps
apache

by biobrain, Jul 06, 2009 12:04PM
Am i active or inactive?

by biobrain, Jul 06, 2009 12:58PM
I have searched a lot of information and bit confused about

Hepatitis B e antgen not detected

Hepatitis B e antibodies detected

To me it indicate that I am a carrier of Hep B but Hep B is in inactive state in my body.

+surface antigens indicate that I am Hep B + . My doctor says there is no need to do any test for Hep B surface antibodies as I am positive.

Any chance of clearing Hep B from body? Can I ever clear Hep B surface antigen?

Should I go for Hep B viral load testing? or not as I already have e antibodies?  

by bberry, Jul 06, 2009 02:18PM
well you have HBV. your e antigen is negative which is good.. you're e antigen antibodies are postive which is ofcourse good. yes you do need to test hbv dna load to determine what your current status is.. you also need to go for a liver function test to find out your current ALT and AST levels.

are you going to clear this virus ? well if you are acute then you are most likely to clear it. 9 out of 10 people go on to clear the virus on their own . the remaing 10 percent that cant not clear it go on to becoming chronic carriers of hbv. chronic carriers are most likely to have this virus in them for life as there is no cure for it currently.. no one knows if there's gonna be on in the near future or in the future all at once.
for now there are proper treatment that help contain the virus and keep it at check. in may many case however, treatment is not suggested or required.. in your case with e antigen negative and e antigen antibodies postive you are most likely to go on monitoring and wont be in need of treatment provided that your ALT/AST are in range and that your DNA levbel does not exceed 2000 IU/mL. you will learn more abojut your condition as you go on.. do not panic..most people live normal lives with hbv.. just learn more about your own casse and condition as every case seems to be kind of unique from the rest. ask question - many of them - to your doctor and ofcourse learn what to eat and what not to eat.. if you drink then stop completely as it is the number danger for heppers.

ask more questions if you need . someone here will be able to help i am sure.. good luck and you do the rest of the tests needed to better undersrand your condition

good luck

by biobrain, Jul 06, 2009 03:27PM
To: bberry
I have given my blood sample today for pcr test to study viral load.

May I know (as my e antigen is negative which is good and i also have e antigen antibodies) is there any chance that my viral load will be high or low? I know precise i will come to know after the results .

I do not know the exact figures but my LFTs done for other reason last month were normal.

What you thing am i an active carrier ? or passive ?

Is there any chance I can clear it? and how much time it may take to clear it?

by bberry, Jul 06, 2009 04:09PM
is there any chance that my viral load will be high or low? I know precise i will come to know after the results .
- NO, there is no way u can tell.. hope for a low number  below 2000 IU/mL :-)

What you thing am i an active carrier ? or passive ?
- NO CLUE, your hbeag negative and hbeapostive which "usually" mean good but like i always say every HBV is a unique case.

Is there any chance I can clear it?
- hmmm i'd like to say yes but ......there isnt a cure for this so im afraid the answer is no - for the time being at least

and how much time it may take to clear it?  
statistics show that every B hepper has a 0.05% to 2% chance of spontaneously clearing the virus on their own every year . not the greatesrt percentage but it isnt zero so there is hope. i wouldnt hold my breath though

by biobrain, Jul 07, 2009 02:37PM
To: bberry


Should not my doctor test presence of Hep B surface anti bodies in me? or there is no need?

by britgirl477, Jul 07, 2009 02:50PM
To: biobrain
If you are diagnosed as a chronic then there is no need to test for Hep B surface antibodies (anti-HBs) as you will no have them. They usually appear a few weeks after the HBsAg has cleared and that will only happen if you clear the virus naturally, which chronics don't do.

You need to find out your HBV DNA number as this will tell you whether you need meds or not.
Brit

by biobrain, Jul 07, 2009 05:35PM
To: britgirl477
I have

Hepatitis B e antgen not detected

Hepatitis B e antibodies detected

does this no imply that I have a low viral load? and do not need any medicine ?

by bberry, Jul 07, 2009 06:00PM
To: biobrain
actually i might have to correct brit on that
you do need to always test for hbsab as the presence of hbsab does not neccessarly mean clearance of hbsag. some peope ( i,e..stevenyr ) will develop surface antibodies while till hbsag postive.

this virus is very unique and thats is one f the biggest reasons why doctors dont have it figured out yet.. still more they dont know about it than what they already know.. with it is uniqueness it makes every chronic B hepper a unique case as well.

by britgirl477, Jul 08, 2009 10:50AM
To: bberry
goodness me bberry I never knew that. So Steven is chronic but has developed anti-HBs? How has that happened? Is that not quite unusual? Wow. Well I continue to learn each day on this forum.

So what does that mean for a person who does this?If they have the anti-HBs are they any more likely to clear the virus on their own or does it not really mean naything too much?

I guess it's like acutes who clear they HBsAg but don't ever produce the anti-HBs. You are right, it is a weird and mysterious virus, but I know the docs will suss out the wee sucker soon.
Brit (ever happy to be corrected)

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