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Hep Be Ag (-), Hep Be Ab (+), what does it mean?
by jsw4u, Feb 13, 2008 08:40PM
Cut and paste paragraph from the CDC:
"Hepatitis B e Antibody (HBeAb or anti-HBe): produced by the immune system temporarily during acute HBV infection or consistently during or after a burst in viral replication. Spontaneous conversion from e antigen to e antibody (a change known as seroconversion) is a predictor of long-term clearance of HBV in patients undergoing antiviral therapy and indicates lower levels of HBV."
Isn't this what has happened with me? I went thru antiviral therapy, Interferon, years ago. (see previous forum posting 10 mins ago). I know that since I'm still Hep B s Ag positive, I'm still infectious, but isn't this e antigen (-), e antibody (+) a good thing? Surely, this non-MD is wrong that the presence of the Hep B E Antibody is a sign that I'm "highly infectious".?
Please help me understand this. Thank-you.
"Hepatitis B e Antibody (HBeAb or anti-HBe): produced by the immune system temporarily during acute HBV infection or consistently during or after a burst in viral replication. Spontaneous conversion from e antigen to e antibody (a change known as seroconversion) is a predictor of long-term clearance of HBV in patients undergoing antiviral therapy and indicates lower levels of HBV."
Isn't this what has happened with me? I went thru antiviral therapy, Interferon, years ago. (see previous forum posting 10 mins ago). I know that since I'm still Hep B s Ag positive, I'm still infectious, but isn't this e antigen (-), e antibody (+) a good thing? Surely, this non-MD is wrong that the presence of the Hep B E Antibody is a sign that I'm "highly infectious".?
Please help me understand this. Thank-you.
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It looks like you have chronic HepB (Hep B s Ag positive for over 6 months).
USUALLY eAntibody positve and eAntigen negative is a very good thing because it's indicative of an inactive carrier and would be less infectious to others.
BUT if you need the run the HBV DNA test to be sure.