what does it mean to have chronic non-replicative hepatitis B infection. however there are antibodies against replication?
what should i do if you are diagnose the following: HBsAg- Reactive, HBsAb- Non Reactive, HBeAg- Non Reactive, HBeAb- Reactive and HBeAb(IgM+IgG)- Reactive
In the natural history of. Hepb infection, HBeAg negative is usually associated with a phase in which the virus is not replicative, alt is normal, and treatment is not needed. This should be confirmed by regular hbvdna measurements and liver functions test. This phase may last a long time, however some patients will transition to a active phase because the virus has mutated and will replicate again, causing hepatitis and disease progression. Treatment is then required. So regular check ups are important.
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