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Hepatitis B virus becomes reactive again after being non-reactive
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Hepatitis B virus becomes reactive again after being non-reactive

Hi,

I'm male age 29, and I've been diagnosed Hepatitis B back in 2003 which after treatment the virus became non-reactive.

On March, 2009 I had a blood test for LFT (liver function test) and it showed ALT level as 89 which normally should have been 55. I went to a doctor and he told me that I've gained weight since than so it is due to fatty liver. I took few medicines for a month and after that went again for LFT test but this time all was normal.

Now yesterday I had blood test for Hepatitis B virus and it is showing reactive with a very high value of above 2500.

So now my question is that if the virus has been non-reactive for around 6 years so now  why it has come back? As I had heard that once the virus becomes non-reactive it will not change to reactive.
Also what is the cause behind it and what is the best treatment for it now.

Thanks,
Jaffery
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18 Comments Post a Comment
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Avatar_f_tn
You should re-confirm two things
one what is ur HBsag status and Anti-HBS status.
when first time you cleared of virus , have u taken vaccinations and tested for Anti-HBS?
Now, re-test for hbsag and anti-hbs. if u r anti-hbs is posiive then u r immune to virus.
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Avatar_n_tn
Thanks for the reply. Below are the results of my tests;

Hepatitis B Antigen - Non reactive - 0.346
Cut off rate is 1.0 (test performed by CMIA)

Hepatitis B Antibody - Reactive - 0.01
Cut off rate is 1.0 (test performed by CMIA)

HBsAg - Reactive - 2521 ( patient value)
Cutt off rate is 1.0

Kindly let me know what does the above tests mean and what should be the next step for me regarding treatments.

Thanks,
Jaffery
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Avatar_m_tn
Hello I am Tahir from Pakistan.
I need kind advice from you. One of my relative got the Hepatitis B Reactive.
Cut Off Rate : 1.00
Patient Rate : 2481.41
Method: CMIA

Kindly give advice what should we have to do .
Looking for positive and early response.
I will be thankful to you for this kind favor
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Avatar_m_tn
tahir please send me your personal e-mail i can help you in this regard
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Avatar_n_tn
I recommend to see a doctor at your earliest but be sure to go to some good specialist i.e. hepatologist and not a general physician as most don't have any idea how to treat that.

If you want I can share contacts of few very good specialist if you're living in Lahore.

-jaffery
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Avatar_m_tn
what about your condition what is your status now ? which medcine you used
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Avatar_n_tn
Well the virus is again non-reactive after few months of treatment. I haven't taken the injections but just medicines and still continuing.

-jaffery
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Avatar_m_tn
thanks i am also from Pakistan my condition is similar to you plz help me which doctor you have consulted and which medicine you used and what was your dna level when you started treatment and what at present your hbsag level is ? i heared that once hbsag become reactive it can never become non reactive
at present my lab reports are
hbsag 206 reactive  by eliza method
hbeag        negtive
hbeab reactive
alt 54
hbv dna less than 500iu/ml
ultrasound showed fatty lever as i am over weight
i consulted best hepatologist but they said you are inactive at this stage you do not need any treatment only control your weight and reduce your fats
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Avatar_n_tn
Well to tell you the truth those doctors saying that don't know how to treat it. I faced similar situation and consultant 3-4 doctors all said same but the fact is that best is if your DNA shows no virus detected.

If you're living in Lahore you can consult Dr. Ghais-un-Nabi. His clinic is in Doctors Hospital. He's the best hepatologist that I've seen so far. You must visit him at least once.

-jaffery
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Avatar_m_tn
thanks for information at present this is not possible for me to come to lahore any other good advise if you can give me because my first goal to make DNA shows no virus detected in your opinion in how many time i will achieve it and if once become non detected than it will remain non detected ?plz help because i am loosing too many job due to this low hbv dna
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Avatar_n_tn
Well in my case it just took 3 months for the virus to clear out. I'm still taking the medicines and it has been almost a year now. For how long I've to take the medicines? well the doctor said that it's for life time to keep the virus suppressed otherwise it will create complications if I discontinue the medicines.
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Avatar_m_tn
i am using tenofo b( tenofovir ) from last three weeks which medicine you used doctor give me same advise that continue it plz give me some detail and usefull information what was your dna viral load before taking medicine and also name the medcine
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Avatar_m_tn
i am using tenofo b( tenofovir ) from last three weeks which medicine you used doctor give me same advise that continue it plz give me some detail and usefull information what was your dna viral load before taking medicine and also name the medcine
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Avatar_n_tn
I exactly don't remember the viral load but the doctor told me that it was high.

I'm also taking tenofo b but along with eteva 0.5 mg and folic acid. Besides that I've also reduced the use of sugar.

-jaffery
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Avatar_m_tn
can you give me the contact number of Dr...plz
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Avatar_n_tn
marry584 below is the contact info;

Prof. Dr. Ghias-un-Nabi Tayyab
Doctors Hospital, Lahore
042-111-22-33-77
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Avatar_m_tn
thanx alot....

can u tel me about your HBV DNA report....when you start treatment....?
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Avatar_n_tn
My HBV DNA is clear now it says no virus detected. It took almost 3 months to clear.
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