My mother is in Vietnam and she need help with this test result:
Hbsag: 1.87x 100000
She has hepatitis B for more than 2 years. She took Baraclucle 0.5 mg for 6 months but stopped for more than a year due to some redness reaction in her body. Can she continue to take this drug? For how long if she continue? Please help my mom about treatment because she did not understand any of these and she does not have much help from the doctors in her own country. Any advice is very appreciated.
Hbsag: 1.87x 100000
you got it wrong, check carefully hbsag cannot be reported with this number with no assays, that number of hbsag cannot be reached with any unit or test.recheck and post complete number and unit
don t say much except that virus is active and liver damage too
baraclude cannot be taken for 6 months, just useless and dangerous, this drugs takes from 6 months to years to just start activity and must be managed by a doctor who knows both drug and hbv, the current doctor doesn t.
to some redness reaction in her body, never reported for entecavir, probably not due to entecavir and even if so no doctor will discontinue this but switch to another drug
she must find a good liver specialist from what you posted she didn t see any doctor, it is not possible to manage hbv on a forum without an expert doctor
you might inquire here for expert liver specialists in vietnam so that they can manage hbv treatment possibly by tenofovir instead of entecavir (avoid antivirals like lamivudine, adefovir, telbivudine,clevudine, not potent enough)
Yes I posted wrong the test result. It is the test of HBV-DNA with the result of 1.87x 100000. That is her last test result. The following are her previous results:
Dec, 2007: hbv- dna: 9.46x 10000 copies/ml
June, 2008: hbv-dna: less than 500 copies/ ml
April, 2009: hbv-dna: 2.74x 1000 copies/ml and AST is 37, ALT is 58
......, 2009: .............: 600 copies/ml
Aug, 2009: 1.34 x 100000 copies/ml and AST is 41, ALT is 76
Dec, 2010: 1.87 x 100000 copies/ml and AST is 147 , ALT is 98
She has just started Baracluce for two days. Should I told her to stop it and change into tenofovir? I do not no they have it available in Vietnam. Do you know how much it may cost? What is your advice on this? I need some guidance. Thanks a lot.
baraclude is ok, i am on it too because i have weak kidneys, she must check that hbvdna gets to zero by 6 months possibly
it is very important she was not exposed to any other drug before and the best managment would be resistance test before hbvdna gets to zero because baraclude doesn t work if there are lamivudine mutants.but i don t think this test is available there so she might just check that hbvdna gets to zero by 6 months and then monitor every 3-6months to stay zero and never stop the drug
tenofovir should be cheaper than baraclude, the names of tenofovir drugs are: viread from gilead, tenvir from cipla and tavin from emcure
these drugs will not eradicate hbv but just stop any liver damage and progression to liver cancer or cirrhosis, to have some chances to eradicate hbv baraclude or entecavir must be comboed with nitazoxanide as shown n our posts or interferon, interferon can have heavy sides so nitazoxanide would be the best choice and also the drug tambui took might help
if hbvdna doesn t get to zero by 6 months it is better to combo with tenofovir 2-3 months and then use tenofovir only.tenofovir is the most potent with zero resistance, baraclude 1,2% resistance if there are no lam mutants (with lam mutants resistance is very high)
Do you know anything about a drug name: Planovil (300mg)- supposed to use for hepatitis B and HIV?
My mother is taking Braclule and her doctor in Vietnam change her drug using Planovil. I am so confused and can't find it online.
Planovir does contain Tenforvir after I checked it out. Its ingredient is Tenofovir disoproxil fumature, 300mg. It is used for HIV and Hep B patients. I assume that it is Tenofovir. Please correct me if I am wrong.
Do you think it is ok to switch drug like that? Does she has to take calcium with it? When she should has to check her BUN? Can she take multiple vitamin with it? Does she has to take with an empty stomach?
yes it is the best especially in combo with lamivudine like the other member from vietnam, of course lam must be never taken without tenofovir because it makes resistance while tenofovir makes no mutants or resistance ever.remember to check creatinine because on kidneys already damaged tenofovir increases creatinine and kidneys damage while it is perfectly ok with healthy kidneys
Does she has to take calcium with it?
no better take vitamind or daily sun exposure, in case she takes vit d she needs to check calcium and vit d level every 6 months.
should has to check her BUN?
no not bun but creatinine
Can she take multiple vitamin with it?
i'd take alinia (nizonide500) instead of vitamins.vitamins are useless if she had a good diet, only vitamin e 300/400iu and vitamin d have had results increasing immune response to hbv.also selenium and zinc are ok and it can be obtained eating 2 or 3 walnuts a day
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