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Here are my results:
HBVDNA

> 110000000 IU/ml
> 640200000 copies/ml
The method used for HBV DNA Viral Load PCR is COBAS TaqMan HBV Test.
The detectable range with this method is 6 - 110,000,000 IU/ml
(35 - 640,200,000 copies/ml).
The quantification is homogenous for all HBV genotypes tested.

SGPT/ALT 222.39 U/L
SGOT/AST 67.23 U/L

AFP (ECLIA) 2.53 IU/mL

chronic hep B
31 years old
Male
chinese

my ALT has spiked from last year's test of less than 40 to 222 this month
i haven't been taking anything for it yet because my SGPT was previously very low.

my brother has similar numbers (except his ALT is constant at 139 for 2 years now)
my brother has been taking Clevudine (Revovir) for 120 days now.  his HBVDNA is unchanged at >640,000,000
my sister i think has taken entecavir and is reportedly responding very well to it.

i will of course consult with my doctor, but am surprised that revovir is not even mentioned in the Hep B welcome page.  any help or opinion that doctor's don't normally tell the public?

thanks
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3 Answers
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Avatar universal
Clevudine (Revovir)
clinical trials have been stopped because of very severe sides (possibility of losing movment/walk and muscles, ) so the drug has never been produced or upproved unless some asian countries where even poisons can be approved
it has also a very high mutation percentage, poor results and resistance to hbv drugs...so it must be stopped immediately
http://www.medicalnewstoday.com/articles/146749.php

with such high hbvdna, which are common for asians, the best and safest drug is tenofovir since it makes no resistance and no mutations

entecavir is safe for your sister only if hbvdna become less than 12 or 6iu/ml by about 6 months, guideline accept also 12months but that is ok if hbvdna is already very low after 6 months like less than 100iu/ml.if this is not the case i'd be worried for resistance

alt/ast has no meaning and are very poor to show liver damage they must be normal (less than 3o men less than 19 women) with hbvdna undetactable or less than 2000iu/ml
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thanks for the reply!

so entecavir has no chance for mutation, only resistance? (what happens after resistance?)

i will ask my doctor about tenofovir.  (no resistance and mutations, sounds almost too good to be true) :)

we did some research on revovir, and have seen the muscular side effects but i don't think we knew about the chance of mutation.

yes, it's too bad that what's prescribed over here seems to be which has the best commission for the doctor.
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so entecavir has no chance for mutation, only resistance? (what happens after resistance?)

it has chances but very low

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