How long did it take some of you to get "undetected"?

[luckyman316]

As I approach my month 7 labs, as of month 6.. I was still not undetected. I've read some people it happened after 5 months, some after 6, some after 8 and some a little over a year. So curious to know how long it took you to have undetectable viral load while on medication (and which medication was it). Just trying to figure out the average time. My doctor suspects mine will take about a year. So far, he's been spot on about everything.

[mac790]

Right you are, I just responded to the "**" members are looking for help from you. My bad for not checking the header. And a lot of wasted typing.   mac

[bigmoviebuff]

about 260,000
my ALT,AST took a bit longer to come down.

[stef2011]

you got wrong community, this is hbv not hcv.we dont use hcv drugs and we dont use viral load as clearance of virus because hbv is very different from hcv and integrated in human genome, hbv needs no virions to make the infection, hcv is a much easier virus with no dna integration

[ono8ono]

do you recall the HBVDNA count before taking viread? Thank you.

[bigmoviebuff]

luckyman,
i was on viread and became undetected after 3 months.

[mac790]

luckyman316,  I don't want to be the bearer of bad tidings, but we need some more info than you have provided. What treatment are you on?  The facts are this, as far as I know: Back as far as 2009, when the gold standard of HCV tx was PEG-INF and RBV, if they did not see a "log 2" drop in your VL, you were considered a null responder. Log 2 drop would be going from 600,000 to 6,000. Just go two decimal points to the left of whatever number you started out with, and then check your latest VL. I know because I was terminated from tx because if you did not achieve this milestone at the end of month 3. If you are using any of the new generation meds, from Sovaldi all the way up to various combos combos with that and/or Olysio, you should have seen a tremendous drop off of VL after 2 weeks of tx. I don't want to make you feel bad, but mine dropped using an experimental Merck drug combo from 585,000 to 396 in 7 days. By day 14 it was ND, been so ever since. EOT is either 10-31 or another month after that, I don't know yet. You might want to run it by other members, they may know how long the Sovaldi/INF/RBV tx takes to show significant VL drops. All I know about my trial meds is that they are advanced forms of protesase inhibitors, attacking the HCV's ability to spawn new copies of itself. There is no guarantee I will remain ND once tx stops, the Merck people consider ND @ 6 months > EOT as a SVR. The folks running the trial will monitor me for 2 years > EOT. My guess is that if it is ND 12 months > EOT, it is truly gone. This is a particularly nasty, tenacious little SOB of a virus though, so I suspect I will always feel my pulse quicken when I read my latest VL count. Pls give us some more info, and folks here can give you more detailed answers, OK? Good Luck,  mac790

[stef2011]

i saw etv not getting und by 4-5 months so added alinia and go und by 2 months of combo, when alinia was stopped years later hbvdna got detectable to 21iu/ml so added tdf to etv for 2 years

now i am on tdf mono and perfectly und

i would not wait more than 6-8months to get und, it doesn t make sense to waste time, add on etv+tdf will make und all hbeag neg.when fully und for about a year on the combo tdf mono can be used and will stay und