I have had Hep B since I was young. Now I have had it for more than 20 years. My Hep DNA result is 88 IU/mL; 512 copies/ mL. It is a little bit higher than the one I tested last year. Does it mean my Hep condition is getting worse? Please help me with an answer. Thank you very much.
you might also check your hbsag titter that correlates with the amount of cccdna in the liver cells and it can tell for sure who is inactive carrier
inactive carrier has hbsag 1000-1500iu/ml or hbs 214/323 s/n - hbs 216/273 s/n, this low hbsag can also tell probability of hbsag seroconversion with interferon if hbv becomes active and tx is needed
monitor hbvdna every 6 months at least and alt/ast every 3 months, no tx is required as long as you are inactive, you might try off label alinia to lower hbsag if it is very low and maybe serocovert in about 1 year (it has been tried on few patients and many seroconverted).alinia has no sides and no resistance, at the moment it is used for hcv
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