Thanks a lot for your answers. I talked to a doctor today (not a hepatologist, though), and she said I might contract hep b again if I come in contact with the disease again because of the absence of HBsAb, but that I wasn't contagious now. However, I was wondering about this mutated hbsag: if I had this mutated form resulting in non detection of mutated antiHBs, isn't it logical that the mutated form of the hbsag would not have been initially detected with the regular tests too? I was HBsAg positive for the first six months, and then became negative. Is it possible that only the mutated antibodies are not detectable, and not the antigen?
I appreciate you opinion a lot.
you don t have to worry too much, immunity to hbv is reported even without hbsab in some cases.it might be possible that you had a mutated hbsag so the antibody to it cannot be detcted by the assay for normal hbsab
anyway as long as alt/ast are normal and hbvdna negative you have nothing to worry
I highly doubt that any hospital in my country (Macedonia, South-East Europe) will give me the vaccine - to be honest, I question their expertise, too. Over these three years I've had enough listening to their indecisive explanations regarding my condition:
- my first hepatologist told me that it was great that HBsAg came negative, which according to her, meant that my immune system disposed of the virus. Then, when she saw that there was no Anti HBs, she said that the virus might exist somewhere in my body, but was not excreted in the blood. She suggested I have the test after 5 months (because they wouldn't get the reagents needed for detection - our health system is an utter disaster). I decided to consult another doctor, because I wanted to start dating, so the other doctor told me that I might have Hep C since HBsAg was negative as was my Anti HBs. Frightened to death, i did that test, which came negative. I turned to another doctor, who said that I am perfectly healthy (meanwhile my ALT was 10 and the ref. value was 9-50 for women). She also said that some individuals dispose of the virus, but never develop anti HBs. A fourth doctor said I should wait for years for the occurrence of Anti HBs SO I WAS SICK AND TIRED OF EVERYONE and after sleepless night spent surfing the net, I decided to do the PCR (DNA of HBV by amplification) at The Macedonian Academy of Sciences and Arts. The Ph.D there said that by amplification of the virus there was no chance of not detecting even the smallest quantity of HBV. It showed ABSENCE OF HBV in my blood. I was relieved until yesterday, when my year-and-a-half boyfriend's results came HBsAG negative, AntiHBs positive, and AntiHBC positive. He never had any symptoms or problems, plus he is a blood doner, so now I'm in for a lot of sleepless nights worrying what happened and If he had the virus from me (thank goodness he isn't HBsAG positive, otherwise I would die knowing that I had given him this painstaking disease for life).
Sorry for writing an essay on my issue, but I honestly hope that I will get some answers, taking into consideration the fact that I am from, and live in a country where diagnostics is an abstract science.
My Best
you can make hbv vaccine to make hbsab and try alinia+hbsab
as to hbv you should make a test so sensitive to get hbvdna till 0-6iu/ml a normal sensitivity test is not helpful in your case.you might even donate blood if you know they check for hbvdna nat but don t tell you have hbcab pos otherwise they don t accept your blood
NGI (national genetic institute) california has hbvdna test with highest sensibility
you can make hbv vaccine to make hbsab and try alinia+hbsab
as to hbv you should make a test so sensitive to get hbvdna till 0-6iu/ml a normal sensitivity test is not helpful in your case.you might even donate blood if you know they check for hbvdna nat but don t tell you have hbcab pos otherwise they don t accept your blood
NGI (national genetic institute) california has hbvdna test with highest sensibility