Is inactive carrier contagenous ?

[sorte]

I suppose approach changed during a years. If person for example is HBsAg+, HBeAg-, HBsAb+ and no detectable HBV DNA in blood is he contagenous ? Any links to confirm/reject this ?
As I red, 10 years ago HBeAg+ was considered that person is always not contageneous, what is not true.

[stef2011]

we are more bacteria and viruses than human.....also herpes viruses, cmv, ebv and so many others are just immune controlled.

we are also full of beneficial retroviruses

[sorte]

So its more complicated than I thought, I didn't know that person who healead after accute infection produces/has any viruses or has hbv dna. At least in my country (Poland) person who healed after accute infection is treated as healthy person who didn't need any more care/checkings etc.. and is treated as non infectious, he just can't be blood/organ donor.

[stef2011]

yes and yes

[sorte]

Thanks for the explanation, I read a lot but I'm still new in that topic.
I know that we know nowdays that HBeAg is just help with diagnostic, it doesnt mean if someone is infectious or not.
So even after HBsAg loss new viruses are produced, they just are controlled by HBsAb ?
Is it the same state as after accute infection ?

[stef2011]

How about after spontaneous seroclearance when HBsAg becomes minus ?

you are confusing with hbeag, hbeag has no real importance today whatever hbeag the infection is still present in liver and blood and transmission still possible by blood injection or organ transplant

the goal today is hbsag loss but as i posted earlier blood and organs remain infectious whole life but this is of zero importance to us when we lose hbsag and make hbsab we have immune control, no new cells infections (hbsab closes entrance to cells for hbv) and no damage.

[sorte]

I see. How about after spontaneous seroclearance when HBsAg becomes minus ? Probably in that case risk is mininal if any ?

[stef2011]

check older posts and how hbv works.

hbvdna is und in blood for sensibility of the test only, it doesn t mean there are no virions in the blood and liver.it means virions are very low not to make liver damage or make resistance to the old weak antivirals.hbv may not be present in semen though so risk by sex is low, by blood always high

did you notice blood is never accepted whatever chronic carrier or immune to hbv infection, transplant is now accepted because even if you transmit hbv antivirals can suppress virions

[sorte]

but how someone who has undetectable HBV DNA in blood can transmit it ? Or it exists always, just is under some levels ?

[sorte]

someone healed after accute hbv as well ? really ?

[stef2011]

any hbv carrier can transmit hbv.by blood and organ transplant even after acute hbv or hbsag loss

most of hbv knowledge of 10years ago is wrong and was not even backed up by studies, just guesses at that time but to say hbeag neg not contagious was ridiculous even at that time

[sorte]

sorry, correct is:

As I red, 10 years ago HBeAg-, HBeAb+ was a sign that person is for sure not contageneous, what is not true.