Hepatitis B Community
Is it possible to have HBsAg POSITIVE but Anti-HBc Total NEGATIVE?
About This Community:

This forum is an un-mediated, patient-to-patient forum for questions and support regarding Hepatitis B. Topics in this forum include but are not limited to, Causes, Diagnosis, Family and Relationships, Living With Hepatitis B, Research Updates, Treatment, Success Stories, Support, Symptoms.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Is it possible to have HBsAg POSITIVE but Anti-HBc Total NEGATIVE?

Does somebody who is surface antigen positive (HBsAg positive) always have Anti-HBc Total positive also? Or can they also be Anti-HBc total negative?

Thanks
Related Discussions
3 Comments Post a Comment
Blank
Avatar m tn

hbcab igm is always negative on cronic (chronic) hbv and if you mean hbcab igg negative it doens tmake a big difference because even if positive the titer is very low

what really matters on hbv infection is:
hbsag quant in iu/ml (i bet this is inversely correlated with nagalase enzyms)
hbvdna

all the rest is not very important since immune response is suppressed by hbsag and there are very low/undetectables antibodies anyway
Blank
Avatar m tn
Thanks for that but I didn't quite understand. Is it possible for a patient to be HBsAg POSITIVE but Anti-HBc Total NEGATIVE?
Blank
Avatar m tn

there are cases in hiv pos/aids patients with a lot of hbv mutants without hbcab and/or without hbsag too, that's due to many mutations of hbv with a very weak immune system

in any case variants are possible in hiv neg too, hbsag negative hbv is more common than hbcab negative

if you google hbcab negative hepatitis b you might find some articles
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis B Community Resources
Top Hepatitis Answerers
Avatar m tn
Blank
stef2011
Italy
Avatar m tn
Blank
StephenCastlecrag
Australia
Avatar m tn
Blank
sorte
Poland
Avatar m tn
Blank
Jatashankar
India
Avatar m tn
Blank
Aduiski
Other
Avatar f tn
Blank
twinboys1girl4me