Isis antisense targeting reduces all markers in HBV
Many companies have come to the table, first one with the cure gets to turn out the light. I think that one of these treatments will find success in the next 4 years and end HBV for those who suffer from it.
- Chronic HBV infection is one of the most common persistent viral infections in the world. Currently available therapies, although effective in reducing circulating HBV in the blood, do not efficiently inhibit HBV antigen production and secretion, which are associated with poor prognosis and increased risk of liver cancer," said Dr. Stefan Wieland, assistant professor of experimental virology at The Scripps Research Institute. "These data are encouraging as they demonstrate that antisense drugs are able to efficiently reduce HBV-associated antigens as well as circulating HBV in an animal model of disease. As such, these results provide support for the development of ISIS-HBVRx for the treatment of patients with chronic HBV infection."
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