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Itch and Rash
I am HBsAg and HBseAg positive with minimal inflammation, low AFP, >100 million viral load. I developed a wicked rash over my trunk and neck a month ago. Dermatologist scraped and thinks its drug related.

Now its over a month and theres a rash here and there. Rash appears and then becomes ring like. Doesn't look like ringworm but not sure. Does anyone have an experience with this? Is this something to be concern with? I started Interferon 2 weeks ago and due for labs in 2 weeks.
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751470 tn?1268502109
from their package insert:
Skin rash can occur in patients taking PEGASYS. In some patients a rash
can be serious. If you develop a rash with fever, blisters, or sores in your
mouth, nose or eyes or conjunctivitis (red or inflamed eyes, like “pink eye”),
stop using PEGASYS and call your doctor right away

and also something that is not so serious:
Skin reactions: Some patients may develop rash, dry or itchy skin, and redness and
swelling at the site of injection.

I quote again "Chronic hepatitis B patients experienced transient acute exacerbations (flares) of hepatitis B (ALT elevation >10-fold higher than the upper limit of normal) during PEGASYS treatment."

Go to your gastro-/hepato- doctor. I think he will ask you to get LFT done now, at the very least, to see if an ALT flare could be the cause.


I had dry and itchy skin, but never a rash.
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