My New Test Results after 2.5 months of starting Entecavir

[SafiSifa]

Dear Friends,

You will see my test results before and after Entecavir in a time line. There is a big change in HBV-DNA and HBEAG.

I will go for fibroscan on the following Tuesday.

PS. I have a very healthy life style, low fat ratio (9-10%), and a fit body. Plus, my age is 29.

Dear Stef2011 and Other experienced friends, please share your comments.


NO TREATMENT


AUGUST 02, 2013 (No treatment)

HSBAG: 438 (not quantity)
HBEAG: 912 (not quantity)
ALT: 197
Bilirubin: Normal
Albumin: Normal
Ultrasound: Normal


SEPTEMBER 30, 2013 (No treatment)

HBEAG: 882 (not quantity)
HBV-DNA: 557 million
ALT: 86
AFP: 2.5
Bilirubin: Normal
Albumin: Normal
Fibrosis: 3
HAI: 11


START TAKING ENTECAVIR ON NOVEMBER 18, 2013


DECEMBER 11, 2013 (1 month after starting Entecavir)

ALT: 100
AST: 57
Albumin: Normal
Bilirubin: Normal


JANUARY 21, 2014 (2,5 months after starting Entecavir)

HBSAG: 530 (not quantity)
HBEAG: 7.4 (not quantity)
HBV-DNA: 122 000
ALT: 91
AFP: 2
Albumin: Normal
Bilirubin: Normal


SUMMARY OF 2.5 MONTHS
HBSAG
Before: 438
After: 530

HBEAG
Before: 912
After: 7.4

HBV-DNA
Before: 557 000 000
After: 122 000

[grmr]

c'mon we're all here to listen, read, share and give opinioins / suggestions.. :)

[SafiSifa]

I love this forum (I mean the community) a lot. Starting from the leading of Stef, everybody try to help each other. We are like a big family!

Thank you everbody.

(I am a little bit emotional because I got  two good news on decrease in HBVDNA and low level fibroscan at the end of the last 6 months with a full of bad news )

[grmr]

if you google you will see 3-7kpa is normal range even for non HB carrier...

any how i found this table...

http://www.sosfegato.it/forumhcv/img/scala_fibroscan.jpg

[afif120]

My son's fibroscan result in Dec 2012 was 6.8kpa...started treatment using viread June 2013.....laboratory result in Dec 2013 indicates HBsAg quantitative declines significantly, HBV DNA declines significantly although not yet UND, fibroscan result 5.5kpa...

[stef2011]

6.6kpa is not even a value to get in to therapy or to be concerned about, it ll get to less than 5kpa anyway

[SafiSifa]

The doctor wrote f1-f2 on my report.

How long does it take from 6.6 to 5.0 with anti-viral+healthy diet?

And is it possible to go to over 6.6 even anti-viral+gealthy diet?

Stef thank you a lot. You are so helpful.

[stef2011]

it is useless to keep refering to old scales with very little meaning themselves, what is f1?how does it correlates to health?this scale is just arbitrary fixed....

this is a scale with some reference 5kpa is normal, 7kpa is significant fibrosis with increased cancer risk, 12kpa is cirrhosis

most normal population with bad diets made of processed foods is around 6kpa

[SafiSifa]

Dear Stef. Does 6.6kpa mean F1, F2 or F3 ?

[stef2011]

of course it is, biopsy was probably wrong

as you may know biopsy takes such a small piece of liver that he just can t say how the whole liver is

[SafiSifa]

Hello Stef,

What do you think, is it a good (healthy) result for the beginning -6.6kPa?

You know my biopsy redult was fibrosis 3.

[stef2011]

very low fibrosis

if the fibroscan is done while alt were elevated in the last 6 months it is best to have a follow up fibroscan when alt are normal and hbvdna und, the next fibroscan will be probably around 5kpa

[SafiSifa]

Fibroscan Results

CAP
Median: 198 db/M
IQR: 32
IQR/med: 16/100

E
Median: 6.6 kPa
IQR: 0.3
IQR/med: 5/100

share your comments please.

[SafiSifa]

I am in the hospital waiting for Fibroscan

[stef2011]

too early to comment response is hbvdna undetectable and you have not reached it but that s normal antivirals require from 6 to 12 months, very few respond by 1-3 months already

[SafiSifa]

Dear Stef. Thank you for your sharing. However, I know the story of Entecavir-Tenefovir clearance vb. What I want the forum community to evaluate the data given above.

Unfortunately, I could not find HBSAG quantity test.  I think they even do not know about HBSAG quantity test. :(

[stef2011]

please report hbsag and hbeag as positive/negative, so new members might not be confused by those numbers.also try to find quantitative tests, using the qualitative for chronic carriers is useless

as to hbvdna it will be important to reach undetectable status by 6 months possibly although some patients may take even 12 months.the danger of developping resistance is high if hbvdna is still high after 6 months of entecavir

also why use entecavir if hbeag is postive?it has 5% hbsag clearance if not less while tenofovir has 16% hbsag clearance by 3 years and 0% resistance

[SafiSifa]

Stef, MustThinkPositive, and others. Where are you?