no it is 50% by 48weeks peg add on, 30% is the response to peinf monotherapy when started with hbvdna undetectable naturaaly and not by antivirals
your chances will depend on hbsag quant too, if hbsag is less than 1000iu/ml when you add on pegintf the hbsag clearance chances can be even higher
After stopping etv, I relapsed after 1yr. Now im on tdf and was told by my dr I need to be on tdf forever till hbs seroconversion (which is almost like impossible I know). So he said the other chance I can give myself is to add on peg after 1-2yrs und. But this is just a 30% chance he said.
All of this data regarding nucs btw is just a report.
We need to demand the release of drugs that work Now. That should be the focus. Enough said on Etv Tdf and interferon.
Rep9 gs9620 - immune system therapies. Detox the body. That is what we need to focus on.
news is the no mutation was reported .....
resistance is the right word, mutations accumulate anyway all the time.
i think all the study is just supposition and not a good study at all.
to say no resistance you need ultradeep sequence, the normal resistance tests are too weak sensibility and detect mutations only when most population has the mutant, let s say more than 20%, plus to see this you need years
to me it is just a clinical report with observations with weak tests and too short time which can be considered within china but not in western countries.
guidelines for hbeag neg have the goal of hbsag seroconversion now they dont even consider a stopping for nucs
I don't know is this is elated to running out of money.
judging from this abstract, it can be say that more people will start NUC's and stop after a period of time, so some how the money will increase in the immediate period.
anyway, all this are only supposition, but I consider the the good news is the no mutation was reported .....
i think there are countries running out of money........
to stop antivirals on cirrhotic patients you need at least cirrhosis regression to stay safe because hbvdna und in blood is not a good test to reflect what is going on in the liver
http://www.ncbi.nlm.nih.gov/pubmed/23744454