Aa
Aa
A
A
A
Close
Avatar universal

Results after 24 week pegays

hbsag +  
anti hbs neg
hbeag neg
anti hbe +
alt and ast normal since 2005
hbv dna less than 116 copies / ml ( undetectable ) 18 months ago

HBsAg quantitaive from 19 IU/ml to 13.4 IU/ml then 16 IU/ml and then 20.23 IU over last 18 months

Started with
-PEG interferon 180 mcg once weekly  
-Vit D

after 5 inj and ALT 103 which had always been previously normal

After 11 inj ALT 70 and HBsAg 18 IU/ml

After 23 inj peg Alt is 42 and HBsAg is 0.21 IU/ml  quantitative
Tomorrow will have 24th inj

What should i do, continue with pegasys or not
I am tolerating the inj quite well
initially had problems but now well tolerated
Best Answer
Avatar universal
thanks for sharing and very happy for you you pratically cleared lower limi of detection 0.05iu/ml


What should i do, continue with pegasys or not

are you crazy to ask such a question....?

keep 48weeks of peg until good hbsab is reached, hbsag cleared at 24weeks is very good similar to otan result
31 Responses
Sort by: Helpful Oldest Newest
Avatar universal
hbv
I have find a method to submit test to Lahore. Decision will be based on QBSAG quantitative test and Fibroscan. Will do next month inshaAllah.
Helpful - 0
Avatar universal
hbv
Means Rs. 23480 monthly dosage. :( expensive enough.
Helpful - 0
Avatar universal
since hbsag is an inexpensive test, or should be, you may test every month and it should be und by next month.clinically you may test every 3 months

you also better start testing hbsab, if we are lucky it should be detactable by 3 months
Helpful - 0
Avatar universal
Rs 5870 weekly
tell me ur entire situation ... I might be able to help u
Helpful - 0
Avatar universal
pegasys weekly 180 ..by roche. thats it
Helpful - 0
Avatar universal
hbv
Could you please provide me brand of pegasys, which you are using ? Or better you send it to me privately. If you provide details of all medicines quantity power then it will help much. Thanks.
Helpful - 0
Avatar universal
Just had my 24th inj
Phase I complete (6 months)
Phase II starts next week (6 months of pegasys)
dividing it in parts will help psychologically
when to repeat HBsAg quantitative
-1 month
- 2 months
- 3 months
?????
Helpful - 0
Avatar universal
I dont know what doc ll learn from my example

They have their guidelines and they follow those
They often forget guideline just give guidance ... not meant to be followed blindly
U need to make decisions for indivividuals ....
Helpful - 0
Avatar universal
so doctor's now is useless with hepB carriers?
Helpful - 0
Avatar universal
hbv
Are you measuring your BMI ? What's before and during therapy ?
Helpful - 0
Avatar universal
very good choice, hope the doctor will learn the lesson from your example
Helpful - 0
Avatar universal

In touch with a doc but decision  is mine starting pegasys against his advice
Helpful - 0
Avatar universal
yea i have read everything
Spent hours and hours on PEGasys and HBV
Talked to doctors
Know about all side effects

monotoring my mood
Depression
platelet count
Neutrophil count

renal function

In touch with a doc but decision  is mine against his advice
Helpful - 0
Avatar universal
read carefully all tests to monitor during therapy and time for the tests.thyroid function, renal function, liver function tests

platlets are tollerable as low as 25.000-30.000, less discontinue or have a specialist use drugs to boost it

neutrophils are tollerable as low as 0.5-0.7, less discontinue or have a specialist use drugs to boost it

thyroid, tsh,t3,t4 and thyroid auto-antibodies
discontinue if hyperthyroidism happens, very rare
hypothyroidism does not require to stop peg but a specialist is needed and t3 or t4 hormones used according to specilist indication
Helpful - 0
Avatar universal
No doctor.. doing it all on my own
Helpful - 0
Avatar universal
hbv
Congratulation Ali! Even after 4 years i didn't find any good dr. in my city. On which dr advice you are following ?
Helpful - 0
Avatar universal
Pakistan
Only one lab doing test here
Helpful - 0
Avatar universal
Where are you from Ali?

In Turkey, I could not find a place for HBSAG quantitiy test
Helpful - 0
Avatar universal
Its all about effort and hope
I am amazed how most of the hepatitis docs just say ... there is no hope
u have to live with it
Helpful - 0
Avatar universal
HBsAg quantitaive in IU/ml is a good test
Most doctors treating HBV here are unaware of it
Helpful - 0
Avatar universal
hbvdna undetectable very early is a sign of response and if hbsag was low baseline like 1000-1500iu/ml there are chances to clear it

what was the reason to lower pegintf, platlets or neutrophils?getting it back to 180mcg would be best
Helpful - 0
Avatar universal
You are on your way man. Very good result.

Looks like I am 4 weeks ahead of you (week 29th this week) but I am on 135mcg and no clue on my HBsAG numbers. HBV DNA Undetectable.







Helpful - 0
Avatar universal
So generally speaking without being "super specific"  12months nucs 11months peg int = hbsab. is that right?
Helpful - 0
Avatar universal
as you see from other posts too many vairables, hbvdna can be und in 1month  to 12 months and response to peg will also depend on hbsag quant baseline
Helpful - 0
2
Have an Answer?

You are reading content posted in the Hepatitis B Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.