Should I take Viread with these results ?

[calebz]

Hi

Since I am HBeAG negative Viread is not being refunded here - only IFN,lamivudine. I signed up for a clinical trial with combo Viread + IFN. After reading more and more I'am wondering if I should take VIREAD knowing It will be for a finite period of time - a lot of people suggest not to stop taking it because of the viral load spike afterwards.
Question is should I take VIREAD for a finite period of time or go the IFN way now ? I haven't taken any treatment yet.

I am 29 years old diagnosed at Jan 2012. My results are
ALT 53-60
HBV DNA 255036 IU/ml
Fibroscan F0-F1 (6.8Kpa)

Also How long must I wait before trying to conceive a child after Viread or IFN treatment treatment ?

[stef2011]

HBeAG+   what does this mean on my report?

this is very good, you have about 11-16% chances to clear hbsag definitively by 3years of tenofovir

You mean I should ask my doc to start INF with Viread?
no starting tenofovir and pegintf together is not helpful, stay on tdf monotherapy about 3 years and then if no hbsag clearance add on peg

you need hbsag quantity in iu/ml before starting therapy, hbvdna will get undetectable but what it counts for hbv clearance is hbsag quantity

[HBVgone]

I am going to start Viread tomorrow.. You mean I should ask my doc to start INF with Viread?  Or take the Viread first to knock down the Viral load and then start the inf?  i am so confused with all the protocols.  

HBeAG+   what does this mean on my report?

[armita446]

plss could u answer my q?

[stef2011]

just try intf+viread and see if hbsag lowers, viread mono will not work on hbsag but intf+viread has high percentages of response

[calebz]

Yeah the Original post title misleading since I got IFN instead of Viread.

[bigmoviebuff]

sorry. yes.
i only saw your HBsAg results.

BTW, i am HBeAG- and just started taking Viread.
I don't think viread makes a difference whether you are HBeAG-  or HBeAG+

[calebz]

Isn't HBeAG- the same as HBeAG Non-Reactive ?

[bigmoviebuff]

your last test did not test HBeAG. If it is negative before, then it will probably remain negative.

[calebz]

Hello

Just got my latest results. After careful study I'm a bit confused with the HBeAg being Reactive. Does this mean I switched from being HBeAg- to HBeAg+ ?

The rest is
HBsAg Quant 4492,21 IU/mL
HBsAg Reactive
ALT 61
AST 32
HBV DNA 146346 IU/ml

Is DNA that jumpy ? My previous count mentioned in in the original post was made about June. This is October.
Finally I got randomized into Interferon monotherapy. After first dose I don't notice any sides.

[calebz]

Thanks for your reply. I googled up the patent and found some info its going off in 2018 - thats good news for me I guess.

Can you answer my question regarding pregnancy ? Me and my wife are attempting 3rd time after 2 miscarriages. She had autoimmune therapy and we have a green light for 3rd attempt. Problem is that the first 2 attempts were 100% success now its 4 month trying and still nothing - damn nature is against us. The therapy is valid for a finite period of time and this trial can last up to two years. How long must one wait after taking viread until I can safely try again ?

Also thanks very much for your input around here cause doctors around here either don't care and give you standard program for HBV or run clinical trials.

[calebz]

Also "Antygen HBS" is 15,85 index - i don't know how this translates to US standards.