Brief Intro: have been on Truvada for more than 3 years now, switching from LAM (lam resistance, I took lam for 3 years). HBeAg +, AntiHBe - , 25 years old, genotype B.
Ultrasound, fibroscan (around 5.0 kPa) & blood test (AST, ALT, Creatinin,... HBV DNA undetectable) every 6 months comes back normal (been doing this for 5 years now).
I'm thinking about taking Tenofovir only because I will move to a place where Emtricitabine is not available. I know it is better to combo. But can you tell me how risky it is if I take tenofovir only (LAM resistance)? stef2011?
"Risk" is relative. You just have to choose the best option that is available. Given you are resistant to LAM, staying on Truvada is obviously better. But going mono on Tenofovir should be ok given you current UND. Tenofovir has a excellent resistance profile especially in UND situations. Even if you are resistance to LAM, can you access Entecavir as a possible combo with Tenofovir?
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