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The best place for treatment of Hepatitis is India

Hi,

If anyone can suggest me the best place for treatment of Hepatitis B in India? I have tried hard but could not find a hospital is specialised for such treatment.
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Avatar universal
Can you guide me Interferon works at this HBSAG levels?
or should i consider Interferon once hbsag comes down to 1000?

you can use it now and later on too when hbsag gets less than 1000iu/ml, i strongly suggest to combo with vit d 10.000iu daily and gcmaf if you can afford it.the most potent gcmaf is from saisei japan

no use tdf for now
Helpful - 1
7 Comments
Thanks stef. I will research on gcmaf.I hope i can afford.
Hi Kri99 Please help us My wife hbsag value is 483 IU/ML. all test are normal and i am not effected that virus. we dont have any bad hbits. she is handy capped (she met with an accident when hand was broken when surgery report valu is Positive  (7010)  those test are CMIA test. it is cure or not.
coolnaresh

As mentioned by steff in lots of posts,
get the tests done iu/ml.
If you are in any capital cities of india, These tests can be done through LalPath labs.

If you are near to Delhi, Consult at ILBS.
They have all the equipment and most seniors doctors who handling HBV cases.

They can guide you better than me.
Hope for the best

@steff,

I consulted for gcmaf through their website.

This is their reply in mail:

Dear Kri,

Thank you for your interest in our products.

We cannot ship to India and do not have any doctors in that area.

If you can please provide us with an alternative address we can then ship to you.

Everything we know is on https://gcmaf.se/


At the end of the mail in the
disclaimer

I understand I will be taking part in a PRE CLINICAL TRAIL and I guarantee to provide progress reports every 2 months, from which Immuno Biotech will extract data to publish statistics and research papers while protecting my identity as we always have. I have done my own research into GcMAF elsewhere without relying on you, and my decision to take it is mine alone.


Not sure what to do now....
Any one from India in  this community able to get the gcmaf some other way?
Hi kri99 this test from lalpath and value is in iu/ml
Plese Steff Help us
Avatar universal
US is the worst place to get hbv treatment, india is much better especially  ILBS Delhi.it will be hard to find a doctor to cure your hbv and not just manage it

best strategy is to try peginterferon for 24 weeks and if no hbsag response just monitor because your low hbvdna does not require antivirals
Helpful - 1
1 Comments
Very much thankful to stef and brig.


Can you please comment on this .


I visited ILBS delhi this week. Below is my latest report stats.


HBV DNA QUANTITAIVE =>  86,600 IU/ml   (6 months back 139 IU/ml).


HBASG Quantative 3978 IU/mL (6 months back 1183 IU/mL)

vitd25oh  => 84.8 ng/ml (6months back 12.10 ng/ml)

Bilirubin Total =>  3.6 mg/dl( 6 months back 1.90 mg/dl)

Bilrubin direct => 0.3 mg/dl (6 months back 0.46 )


AST/SGOT  => 25 IU/L (6 months back 27 IU/L)

ALT/SGPT => 18 IU/L (6 months back 17 IU/L)


TSH  2.29 microIU/ml

Serum Creatinine => 1.01 mg/dl

Haemoglobin => 18.1 gm/dl
PCV / Haematocrit => 53.9%

RBC Count => 6.09


FibroScan

No: Valid measurments10, successRate 100%

E kPa
Median 6.8
IQR       1.0
IQR/med 15%

CAP dB/m
Median 224
IQR       63

USG Normal. (6 Months back normal)

hbv dna count increased alot(100's of times) in this 6 months.
Can you tell whats the criticality of im in.

Whats the treatment i should look for now.

I have appointment with Doctor tomorrow at ILBS , What and all I need to discuss with doctor.












Avatar universal
Thanks everyone who's answering all question with lots of patience.

Recently I have gone through health checkup and results came out as i am effected with HBV +ve.

Below are my test results.

1)HBV DNA Quantitative  139 IU/mL  (1 IU/ml = 5.8 copies /mL)

2)Anti HBe 0.01 Index

3)HBeAg  0.27 Index

4)Anti-HCV 0.06  Index

5)Anti-HBc IgM  0.04 Index

6)Anti HBC TOTAL  10.66 Index

7)USG (UltraSound abdomen) normal

8)HBsAg Positive

9)
Serum LIVER FUNCTION TEST
   BILIRUBIN-TOTAL (mod.J Groff)**  1.90 mg/dl
   BILIRUBIN - DIRECT (mod.J Groff) 0.46 mg/dl
   SGOT/ AST  (P5P,IFCC) 27 IU/L
   SGPT/ ALT (P5P,IFCC) 17 IU/L
   ALP (p-NPP,kinetic)* 82 IU/L
   TOTAL PROTEIN (mod.Biuret) 7.4 g/dl
   SERUM ALBUMIN (BCG-dye) 4.6 g/dl
   SERUM GLOBULIN (Calculated) 2.8 g/dl
   ALB/GLOB (A/G) Ratio 1.6

10)Serum VITAMIN D-(25-Hydroxy)*(MCIA)  ng/ml

My doctor asked me to visit after 6 months, told no need of any treatment as of now.

Please help me to understand my status and require any more tests to findout exact status and is that curable or not?

Thanks in advance for all your help.





Helpful - 1
1 Comments
I am 33 years old male from bangalore working as a software engineer.

Please let me the best doctor who
treats the HBV positive cases
Avatar universal
What is relevance between vitd and hbv treatment please answer I am very much confused about to start my treatment
Helpful - 0
Avatar universal
I started using interferon last week.
When i got injected first week, I got  fever and joint pains for 2 days.
This week when i took the interferon, I didnt get fever and no joint pains.

Is that expected?

Some one please clarify
Helpful - 0
6 Comments
yes it is expected.on hcv they found correlation between high fever at first injection and response, no such study on hbv
sorry correlation was with very high fever pick, the highest fever got the best response, dont remember if that was for temp over 39°
@steff,

I completed this week 12 injections and went for hbsag Q test and HBVDNA Q test.

HBVDNA Quantitive  <20 IU/ml (3 months back 86,000)

HBSAG Quantitative 3434 IU/ml (3 months back 3978).

Should I continue injections/ Or stop it as HBSAG not reducing much.

or for 12 injections , HBSAG reducing ~500 IU/ml is good sign to continue these injections.


After i started these injection , I became very lean and lost around 5kgs of weight and lot of body pains.

Please let me know whats your view on this






you should wait 24 weeks to tell (12weeks may have yet no response at all) and check that vitd25oh is 80-100ng/ml to ensure best response
Thanks steff, continuing for one more 12 weeks
@stef2011

I  completed one more 12 injections. Total 24 injections are completed as of now.

HBVDNA Quantitive  = 25 IU/ml
3 months back <20 IU/ml
(6 months back 86,000)


HBSAG Quantitative 172 IU/ml.

3434 IU/ml 3 months back .
3978 IU/ml 6 months back).


Should I continue for one more 12 weeks?


Avatar universal
Only Hbv DNA test cannot tell anything. Consult with good hepatologist and do the following test
Hbv DNA which already done
Liver function test
Fibroscan
USG of abdoman.
Fibroscan is most important which tell you treatment is necessary or not
Helpful - 0
Avatar universal
Very much thankful to stef and brig.


Can you please comment on this .


I visited ILBS delhi this week. Below is my latest report stats.


HBV DNA QUANTITAIVE =>  86,600 IU/ml   (6 months back 139 IU/ml).


HBASG Quantative 3978 IU/mL (6 months back 1183 IU/mL)

vitd25oh  => 84.8 ng/ml (6months back 12.10 ng/ml)

Bilirubin Total =>  3.6 mg/dl( 6 months back 1.90 mg/dl)

Bilrubin direct => 0.3 mg/dl (6 months back 0.46 )


AST/SGOT  => 25 IU/L (6 months back 27 IU/L)

ALT/SGPT => 18 IU/L (6 months back 17 IU/L)


TSH  2.29 microIU/ml

Serum Creatinine => 1.01 mg/dl

Haemoglobin => 18.1 gm/dl
PCV / Haematocrit => 53.9%

RBC Count => 6.09


FibroScan

No: Valid measurments10, successRate 100%

E kPa
Median 6.8
IQR       1.0
IQR/med 15%

CAP dB/m
Median 224
IQR       63

USG Normal. (6 Months back normal)

hbv dna count increased alot(100's of times) in this 6 months.
Can you tell whats the criticality of im in.

Whats the treatment i should look for now.

I have appointment with Doctor tomorrow at ILBS , What and all I need to discuss with doctor.

Helpful - 0
4 Comments
I consulted the doctor at ILBS today.


Here is the info/support i got from doctor,

This info is available on the net, But it may be helpful who's searching first time about HBV , who are in early 30's or late 20s, and got depressed like me till i met the doctor.



In Doctor words,

No need to get scared/tensed/stressed because of HBV.

Medicines are there to lower the HBV DNA virus load in the blood and its successfully working worldwide.

For lowering HBSAG , medicines are there , But not 100% gurantee as of now. In the near future it may come as lots of research is going on these in advanced countries.

In my experience seen around 50% of patients get rid of hbsag as well ( I forgot to ask total patients he dealt till now).

HBV manageable treatment is there.

But should be cautioned about liver.

Six months once follow ups are mandatory.

Should be avoided alcohol  totally.

Must have exercise  daily atleast upto 30 min to 1 hour.

Don't put lot of stress on liver by taking lot of junk food.


Proper sleep should be there.

Maintain a healthy life /food.

All family members tested/vaccinated.


Who's following all these , they recovered lot. and also seen patients  who's health absolutely normal at the age of 60 who effected even from childhood.


For me doctor prescribed
TDF 300mg every day one for 6 months.
Pegylated Interferon Alpha 2B(80 mg) once in a week for 24 weeks .

consult again after 6 months with same set of above test results.

And every month  bilirubin, CBC tests should be done and reports send him through mail.

@steff

Can you guide me Interferon works at this HBSAG levels?
or should i consider Interferon once hbsag comes down to 1000?

Doctor didn't mention anything related to D vitamins and also i forgot to ask also.

Should i take 5000 IU D vitamin every day?


and also heard about TAF which is better than TDF. Should i wait till TAF comes to market?

Hi kri.. what all tests have you undergone..can you name them and how much would they cost. I m suffering with hepatitis b since 2007 and never bothered but these days suffering with pain in my **** while pissing. And the urine is in dark yellow color. If you can list out the tests you are undergoing... I ll get all the tests done. Or do you advise me to consult a physician ?
i got it done all above tests, I suggest consult with a doctor
which doctor have u visited? can u mention his name  please ?  i am leaving outside the country .. so i will directly visit to that doctor
Avatar universal
Thanks stef.
I will recheck hbvdna and will post the results here.
Helpful - 0
Avatar universal
hbvdna i didnt test this time , 2 Months back when i tested last time , thats 139 IU/mL.

I am planning to take appointment at ILBS  Delhi next week.

Treatment i am not decided anything yet,  But ready to follow which ever best treatment available as of now in india / USA (If its required i can travel to USA for treatment). But looks ILBS Delhi handling lots of cases now a days in india. Will take opinion from there first.




Helpful - 0
Avatar universal
i just saw your other tests, hbvdna is very low but recheck it to be sure it is still low

i d wait for vitd25oh to get to 100ng/ml and intact pth to go lowest of normal and then think about peginterferon or tdf treatment.vit d needs about 6 months of stable levels at max normal range to have an impact on immune system
Helpful - 0
Avatar universal
your vitd25oh is not optimal, use tsts with ng/ml or ask lab for results in ng/ml unit, you need to reach 90-100ng/ml

With in 1 month, hbsag quantative  almost trippled.What this indicates? What are my next steps?

this has very little meaning, in one month there is yet no chance on vit d levels it takes 6months of stable vitd25oh at 90-100ng/ml and at the same time intact pth lowest of normal
keep taking vit d3 at 10.000iu daily and retest vitd25oh and intact pth by 2-3 months from now

what is your hbvdna now?are you thinking of peginterferon treatment or tenofovir?
Helpful - 0
Avatar universal
@stef2011,

Today my reports came for vitd 25oh and hbsag quantitative

HBSAG Quantative @CMIA :  2979.25 IU/ml
Vitamin D 25 Hydrox Serum
147 nmol/L

With in 1 month, hbsag quantitive  almost tripled.

What this indicates? What are my next steps?

Is HBV increasing so fast is common, or im totally in very bad situation?

Helpful - 0
Avatar universal
Today my reports came for vitd 25oh and hbsag quantitative

HBSAG Quantative @CMIA :  2979.25 IU/ml
Vitamin D 25 Hydrox Serum
147 nmol/L

With in 1 month, hbsag quantative  almost trippled.

What this indicates? What are my next steps?
Helpful - 0
Avatar universal
very lucky hbsag is very low, i suggest you get your vitd25oh to high end of normal before starting pegintf, recheck vitd25oh by 1 month supplementation then as soon as vitd25oh and intact pth are ideal i do for pegintf or pegintf+tdf, also recheck hbsag when vitd25oh is around 100ng/ml and intact pth around minimum of normal maybe it ll go less than 1000iu/ml

not sure you ll clear in one shot but you have highest chances to clear
Helpful - 0
1 Comments
ok thanks stef. I will update the vitd25oh results after 1 month after taking every day 10,000 iu vitamin d capsules.
Avatar universal
not it is not good because vitamin d can t be taken weekly, you must get a 10.000iu pill to be used daily
Helpful - 0
1 Comments
Thanks stef, I will change it to daily pills. HBASG Quantative report has come, it says 1183 IU/mL . So i need to go through treatment instead of waiting 6 months right?
Avatar universal
you are extremely deficient, this level is dangerous for general health and not just liver, you better start vitamin d3 10.000iu daily as soon as possible by 6months you may reach optimum levels
Helpful - 0
2 Comments
stef,

I started  taking CALCIROL 1g sachet with milk once in a week from last 3 weeks.

thats sachet says CHOLECALCIFEROL GRANULES 60,000 IU/gm.

Is this good enough?

HBSAG Quantitive 1183 IU/mL
Avatar universal
check hbsag quant in iu/ml and fibroscan, most important test to define status, if hbsag is low you have highest chances to clear by pegintf.this said pegintf can have very heavy sides but anyway it is possible to try 12-24 weeks and see how it goes

what s your vitd25oh?
Helpful - 0
1 Comments
Thanks alot  stef2011

vitd25oh  12.10 ng/ml.

I will get it done these 2 tests in bangalore itself probably tomorrow.

Avatar universal
Hi consult Dr.Sarin at ILBS hospital Delhi.
Helpful - 0
1 Comments
thanks alot jcm60, Will check this weekend if i get appointment there. I am searching for best doctor for first opinion in bangalore itself.
Avatar universal
evil spammers, wish you get some real disease one day
Helpful - 0
Avatar universal
U r in best hospital. And Dr SK satin is best doctor .please post your all lab result
Helpful - 0
Avatar universal
hi, i was recently diginosed with HEP B +
i am 24 yrs of age.A regular voluntary blood donar for last 6 yrs
i am a student
I visited ILBS in INDIA
My Fibroscan and Ultrasound are normal.
KFT LFT CBC reports are pending.
pls suggest about the hospital and treatment
Helpful - 0
Avatar universal
Is vitamin c may b used in hepatitis b???
Helpful - 0
Avatar universal
Alots of thanks to respected steff and brig and other members for give d brighten way about hepatitis b.....again lots of thanks....always keep touch wid us.
Helpful - 0
Avatar universal
Dear All,

MIOT Hospital Chennai is organizing a seminar in Kolkata on 12th of this month on how to reverse lever damage. A full day Seminar, Free consultation and experts will be available. More detail available on  www.miotinternational.com. May be of some help.
Helpful - 0
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