Was on pegasys for 24 weeks: viral load started at 15 million, went down to 5 million, but recently jumped back up to 8 million. Doctor removed me from pegasys, which was obviously frustrating. During the last 4 weeks of pegasys treatment I really "felt" something in my liver - which I assumed was a good thing, in light of viral load going up am now concerned about "feeling" liver / could also be "worry". Alt/Ast have gone down to about 70 each after peaking at 120 in December. Took milk thistle 3 x times a day, which I credit with bringing down Alt/Ast.
Just started viread 3 days ago and have almost a constant nausea feeling. Apparently this is a commons side effect (googled it). Questions: Any experience with viread nausea? Will nausea eventually go away? When is the best time to take viread? Is it advisable to take milk thistle with viread?
Hello. HBVDNA is 7.2 million - in other words high.
EAG status = +
Liver damage: AST = 68; ALT = 72
Doctor's reason for removing me from Pegasys: sides were very low white blood cell count (hovered between 2.2 and 2.8) and he said with the HBVDNA levels going back up there was "no response" - as the HBVDNA rose again. Had no noticeable sides while taking pegasys though.
Viread side is more like stomach pain + burping - but I think this is largely nervousness. When focusing on something else the don't fell stomach as much. When I think back the unsettled stomach feeling started when they told me I was not responding to pegasys.
Thanks for the milk thistle tip - I had read NOT to combine milk thistle with antivirals like viread. If you have had good experience with milk thistle I will continue to take it. If anything it makes me feel like I am doing something.
the doctor is ignorant switch to another one, high hbvdna is obviously interferon failure for sure
grmr had the same wrong treatment but it was many years ago and so it was not known that hbvdna makes pegintf failure and now he has been retreated with viread first and then peginterferon add on
viread alone is useless to clear hbv especially if you have no liver dmage, the chances to clear hbv are only 16% at 4 years.i do suggest to do the same as grmr find a good doctor, keep viread for 1-3 years and then add on interferon, making viread monotherapy has too few chances to clear
i am on both viread and baraclude so i cant choose.i take viread at breakfast and baraclude before bed
viread is best absorbed by fat meal so depending on the type of meal lunch or dinner may be better
also remember to monitor cratinine before starting viread and then every month first 6 months of vread use
you also need to take vitamin d3 supplements to make sure vitd25oh stays higher than 50ng/ml (optimum levels 80-90ng/ml).this is a must for all hbver because we are all deficent (less than 40ng/ml).this will make viread sides less, will improve immune system resposne and prevent/regress fibrosis/ cirrhosis
check all posts in the forum about vit d3 and all its benefits, taking vit d3 needs also monitoring every 3 months of vit25oh and calcium
yes for now thats the plan with highest hbv clearance, the goal is hbsag<1500iu/ml because add on peginterferon at that low level allows fast hbv clearance in almost 48weeks but also hbsag around 8000iu/ml got to extremely low just adding peginterferon
in may i will start myslef peginterferon add-on (i am 2.5years on etv and 6months tdf)
one last question: had one liver biopsy about 7 months ago, there was damage so they started treatment. how often do your / recommendations for biopsy? invasive i know but what are the guidelines here?
biopsy can t be repeted, there is also a remarkable death risk and liver damage, it is also obsolete.i d never do a biopsy with fibrosis stage 3.
i had 2 in my life but this is one about 10years ago and one 25-30y ago, it is not used anymore
fibrosis is monitored by firboscan only together with US every 6 months
no i'm on viread mono since 4 months and i''ve started ifn 4wks ago.. DNA is dramatically going down under 2000iu/ml.. my docs (who are not followign the very latest protocols) wanted to start a little before DNA gets und..
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