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Treatment of hepatitis B (chronic), inactive?
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Treatment of hepatitis B (chronic), inactive?

Hi, I’m M. Talib and I’m 27 years old now (date of birth is 15/10/1985).  
I am having hepatitis B virus (chronic )in my body that is inactive according to the doctor. Kindly help me.

-->First time test report: (dated on 01/03/2012) :
HBsAg (test performed by ECLIA) ---------Result= reactive (2267)
Hepatitis C antibody (test performed by ECLIA) ------ Result = non reactive 0.107

?Second time test  (dated on 22/03/2012):
HBsAg (test performed by MEIA) ---------Result= reactive (262.54)
------------------------------------------
-->After this a doctor suggested me following further tests:

(I’m mentioning here with results)
Dated on 02/04/2012

1. HBV DNA PCR Quantitative--- = HBV DNA detected in sample, viral load 328 IU/ml

2. HBe Antigen-------------------------- = (performed by elisa) non-ractive 0.034
3. Anti HBe Antibody-------------= (performed by elisa) positive 0.348
4. Anti HDV-------------------------= (performed by elisa) negative 2.527
5. CBC:
--> HAEMOGLOBIN = 15.1 g/dl
--> RBC = 4.8 10E12/L
--> HAEMATOCRIT (PVC) = 42 %
--> MCV = 88ft
--> MCH = 31 pg
--> MCHC = 36 %
--> TOTAL LEUCOCYTE COUNT = 4.3 ×10E9L
--> DIFFERENTIAL LEUCOCYTE COUNT
NEUTROPHILS = 55 %
LYMPHOCYTES = 34 %
EOSINOPHILS = 0.6 %
--> PLATELETS = 196 ×10E9/L
--> MORPHOLOGY = NORMOCHROMIC. Normocytic
6. LFT:
--> S. TOTAL BILIRUBIN=0.49
--> S. Direct BILIRUBIN=0.16
--> S. INDIRECT BILIRUBIN=0.33
--> SGPT (ALT) = 38
--> ALKALINE PHOSPHATATE = 102
--> GAMMA GT = 18
--> SGOT (AST) = 27
7. PI----------------------- = 14.5 seconds
8. Albumin--------------------------= 4.56
9. U/S upper abdomen-------------- = It was found ok
10. Creatinine------------------------ = 0.73
11. BGR (Blood Glucose Random) ------- = 122
12. SERUM TSH------------------------ = 1.11

--> I showed the above reports to the doctor. And he told me that no need to worry because the virus (hepatitis B) in my body is inactive. But I need two tests after every 5-6 months for observation:
ALT & HBsAg

--> The doctor also suggested me to use folic acid (5mg) for one month only. He also told me that in the presence of virus (although it is inactive) I can not do vaccination.

Now After passing 6 months almost, I again tested myself from hospital and my reports are as follows (Dated on 27/09/2012):
--> SGPT (ALT) = 36

-->HBsAg (test performed by ECLIA)= Reactive 2670

Kindly help me whether there is any treatment for or not because after 5 months I'll get married.
Regards,
Robtalib
2 Comments Post a Comment
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Avatar_m_tn
You are HbeAg negative, HBeAb positive, hbvdna 328 iu/ml, and ALT 36. Most likely you are in the inactive phase and most guidelines would not recommend treatment. Yes, your doctor is correct that you should be monitored regularly to see whether your hepatitis re-activates. You may never need treatment or you may need treatment if you develop what is called HBeAg negative chronic hepatitis (hbvdna and ALT will be elevated).

Congratulations on your getting married. Please start your partner on the 3-dose Hepatitis vaccine and practise safe sex until she is confirmed to have developed protective immunity.
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Avatar_m_tn
Stephen Castlecrag brother,  I'm grateful from the bottom of my heart.
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