My dad has been on Truvada for about 6 months now, his viral load has steadily declined however, his most recent blood test is indicate that the medication is affecting his kidneys; BUN Creatine 28.3. He has no prior kidney conditions. I know truvada affects kidney function, I was wondering if anyone else has any additional information / options on this. Stopping the Truvada is not an option, and I am afraid to tinker with the dosage fearing a viral spike. I know the kidney function may be a "trade off" and I hate to say that. We have been been through interferon, lumidivin/hepsera, all with initial success and then after awhile the viral load starts creeping up. The Truvada seems promising I just don't know, and can't find any further information regarding the extent to which kidney function is affected. Any information would be much appreciated. thank you.