Hepatitis B Community
about hep b
About This Community:

This forum is an un-mediated, patient-to-patient forum for questions and support regarding Hepatitis B. Topics in this forum include but are not limited to, Causes, Diagnosis, Family and Relationships, Living With Hepatitis B, Research Updates, Treatment, Success Stories, Support, Symptoms.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

about hep b

i am 32 yrs old. i have HBsAg reactive known by a letter from hospital by blood donation. i got checked by the doctor
& HBeAg in negative and anti HBeAg is positive anti HCV is also negative. my HBV-DNA quantitative report is " SAMPLE IS NEGATIVE FOR HBV DNA". My question is am i having hep b virus and after how many months HBsAg should be non reactive. i  will be greatful to your response
Related Discussions
16 Comments Post a Comment
Blank
Avatar_m_tn

you do have hbv as long as hbsag is positive, hbvdna means nothing.if hbcab igm is negative it is cronic (chronic) hbv, if it is positive it is acute and you need to check if hbsag is not decreasing fast it has become cronic (chronic)

if cronic (chronic)
you need to check hbsag quantity by abbott architect in iu/ml unit, if you find hbsag lower than 1500iu/ml you can easily clear hbv by interferon+tenofovir in 96weeks combo treatment

fibroscan to see if liver is damaged
Blank
Avatar_m_tn

acute hbv can have hbsag positive for 6-12 months, of course checking hbsag quantity can tell you if you are clearing or not and how fast
Blank
Avatar_f_tn
hi..i'm also in same condition HbsAg +ve. Did you get any info or any treatment for Hep-B.
Blank
Avatar_m_tn
Hi Anushaa,

I don't think we have treatments cure for Hep  as of now but we have medicines  to control this Virus. As Stef said above if hbsag lower than 1500iu/ml you can easily clear hbv by interferon+tenofovir in 96weeks combo treatment

Did you check your HBSag, HVDNA ,ALT,AST and AFT ?

Thanks
Charan.
Blank
Avatar_n_tn
hi steff,
           i am kru from india.i am one of the seafarer.doctor found that i am having hbeag.the value is 4.9.i am using tenvir tablet.is it  possible to become the value is below 1.how long it will take .please advice me .
Blank
Avatar_n_tn
If HbsAg 6000 IU/mL how many chances to clear it?
or what treatment need ?
And also HBV DNA undetectable
HBeAg -ve , Anti HBe +ve, ALT: Normal
Blank
Avatar_m_tn
about 30% by peginterferon, hbsag will go slowly down even after peg is finished and 30% is reached by 5 years
Blank
Avatar_n_tn
hi stef  i am kru from india, i am having hbe ag positivie.the value is 4.9....i am using tnvir tablet. how long it will take to below 1.which one is very difficult to bring the value below 1.         hbeag  or  hbsag????
Blank
Avatar_m_tn
hbeag is not important, you have to check hbsag by abbott architect or roches elecsys

how many years on tenofovir?after 3 years you can try to add on peginterferon and you will clear hbeag for sure, hbsag should go down as well
Blank
Avatar_m_tn
In the natural history of hepb, there are several phases. HBeAg positive is the first phase. In this phase, the virus is replicating, viral load(hbvdna) will be high. There may or may not be damages to the liver. As we get older, some will naturally become HBeAg-ve naturally, others may not and there may be ongoing damage to the liver. So doctors will prescribe medication to stop the virus from replicating, thereby stopping further damage to the liver, and even allow the liver to heal. This is a long term process. After several years of medication, HBeAg may turn negative. When HBeAg is negative, the virus should stop replication either by the medication or by our own immune system.
Yes, it is possible to revert from HBeAg negative to positive again, but as stef2011 said, it is not important, the main thing is keep viral load low, naturally or by medication, to stop any damage to the liver. Then we can wait for a cure or more permanent treatment to come along.
Blank
Avatar_m_tn
Very clean explanation.
Blank
Avatar_m_tn
Very clean explanation.
Blank
7951432_tn?1400922437
so hbe at firs+ then naturally or Under treatement become -,so it becomes again + wich means reactivation ,could it also becomes again - naturally or should have treatement?
Blank
Avatar_m_tn
Wish I know the answer. Personally, I think any reversion from HBeAg negative to positive should only happen when a) the conversion was natural in the first place, before development of e-antibodies. Eventually, the seroconversion should be stable with the development of e-antibodies; b) when the conversion was induced by medication and the patients then stop medication too soon. This may mean going back to medication again.

Finally, the re activation that we should keep watch for is when HBeAg remains negative, but hbvdna rises. This is then due to the virus having mutated and treatment is then required.

Hope I got it right.
Blank
7951432_tn?1400922437
Finally, the re activation that we should keep watch for is when HBeAg remains negative, but hbvdna rises. This is then due to the virus having mutated and treatment is then required

so even there is anti hbe?
Blank
Avatar_m_tn
Yes, even when there is anti-HBeAg. The virus has mutated ( a great proportion) to a form that no longer produces HBeAg. This is HBeAg negative chronic hepatitis and was only realized only 10 years ago. It can still be treated very well by all the existing HBV medications.
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis B Community Resources
RSS Expert Activity
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating Control: How to St...
Aug 28 by Roger Gould, M.D.Blank
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
Top Hepatitis Answerers
Avatar_m_tn
Blank
stef2011
Italy
Avatar_m_tn
Blank
StephenCastlecrag
Australia
Avatar_m_tn
Blank
veteranB
CA
7951432_tn?1400922437
Blank
flyinsky
paris, France
Avatar_m_tn
Blank
makeadifferencenow
Avatar_m_tn
Blank
andrey19
Russia