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analysis of my fibroscan result
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analysis of my fibroscan result

My Hbvdna count is 63 IU/ml. I am Hbeag + since the last 1.5 years when i was detected with chronic HBV. My Fibroscan result was 6.2

I am still not taking any antivirals. SGPT was 54 with SGOT 29. All blood reports normal. I just wanted to know is my liver fine? I was having fatty liver too .

secondly does saliva contain HBSAG or is analysed by HBVDNA in saliva as some websites suggest? is my saliva still infectious with this HBVDNA? can i infect any1 with this DNA count?  
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Avatar_m_tn

nothing to worry about because normal fibroscan is less than 6kpa but if you have fatty liver you must change quality of food and improve your vit d levels/oxidative stress level/hdl levels

fatty liver is making your reading of fibroscan higher
13 Comments Post a Comment
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Avatar_m_tn

nothing to worry about because normal fibroscan is less than 6kpa but if you have fatty liver you must change quality of food and improve your vit d levels/oxidative stress level/hdl levels

fatty liver is making your reading of fibroscan higher
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Avatar_m_tn
Thanx Stef2011 for your reply. Can u answer the 2nd part too? And I have reduced my weight and changed my food habits since last 1.5 yrs.
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Avatar_m_tn
no too low and even if you do the people having this kiss must receive so much blood in your saliva and have open wounds in the mouth........all this is very unlikly

plus consider that most are vaccinated today and if not they will clear it because adults

hbsag is not infections, it only suppresses our immune system to save hbv

most patients with hbvdna und in blood are und even in semen
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3156104_tn?1357284795
interesting point arises here Stef ...... Being semen/sperm has DNA only is it quite possible that it carries cccDNA too right? so intercourse may cause transmission of virons even without tissues damage?
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Avatar_m_tn
quite possible that it carries cccDNA too right?

no cccdna can exsist only inside cells, when the cells dye also cccdna gets destroyed.cccdna keeps multipling only by new virions infection and cell division

only hbvdna is infectious, hbsag, hbeag are not
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3156104_tn?1357284795
okz.....

in case patient cleared his Bdna and surface antigen during therapy , there would be no any problem even if cccDNA would be present, as cccDNA is not infectious as per your version even if it replicate its replica would be covalently closed circular dna only? which cant do any harm......plz give some light on it
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Avatar_m_tn
when hbsag is und and hbsab>10miu/ml the infection is over, cccdna is und

even if some cccdna remains (no possibility to detect it because too low) it can t do nothing but wait to be destroyed by cell death/cell division.virions even if formed cannot infect other cells because hbsab blocks entrance to cells, so the virions are killed in a very short time
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3156104_tn?1357284795
Gr8.... Stef in case pt is on therapy his HBV DNA is Undetectable currently with HBsAg levels around 1000IU, pt want to switch over combo IM and antiviral but his ALT is normal, can we stop the antiviral therapy prior to IM combo for some time to raise his ALT? coz ALT should be raised if therapy considered with ifn and antiviral like Tenofovir.

Thanks for continuous and satisfying response.
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Avatar_m_tn
@taj

are you infeceted since birthj? the dna is pressy low for EAG+ve..
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Avatar_m_tn
sorry i dont understand well, combo IM?what us it?

hbsag 1000iu/ml and hbvdna und, best therapy is pegintf, if already under tdf add on peg
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3156104_tn?1357284795

No idea ! came to know at age 27, No any B patient in family or in family history ,  Even vaccinated during early age , no any surgical approach in my historical back ground .

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3156104_tn?1357284795
Combo i mean administration of two drugs at one time ( Immunomodulator- i.e IFN with Tenofovir ) to focus HBsAg , which may work in synergistic manner,One planned to enhance immune system and another to protect from any Viron replication.

What about ALT???? can we stop antiviral drugs for a while to take a chance for ALT surge
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Avatar_m_tn
no keep tdf and increase vitamin d to 90-100ng/ml, no need of an alt flare, if tdf has been taken for long enough to rescue immune response hbsag will be cleared with notmal alt
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