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any updates on GS9620?
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any updates on GS9620?

Are they in phase 2 or 3 now? Seems like very little updates  from them.
15 Comments Post a Comment
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Avatar_m_tn
Seems like they are doing phase 2 http://clinicaltrials.gov/ct2/show/NCT02166047
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Avatar_m_tn
I think the results might be out in September for phase 2 a or b I think
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Avatar_m_tn
It seems a bit disappointed to me since interferon-free drug is obviously favourable and it works nearly 100% in HCV and gs9260 is literally interferon capsule.

There is no point for Gilead to continue this project.
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Avatar_m_tn
we are waiting for hopeful news ..
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Avatar_m_tn
This drug is basically an interferon primer in the body, it has value but likely will not increase interferon production enough to match current injectables.

I think this may be beneficial in conjunction with Nucs and ARC-520 to provide a cure once ARC-520 is approved.

ARC-520 is the key and we should be seeing phase 2a knockdown results by end of next month, better that 80% at 2 mg/kg would be very positive
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Avatar_m_tn
The results of the phase 2 clinical trial were disappointing, especially when compared to the data reported on its use on chimpanzees. However, I hope a phase 3 will proceed as recommended. Being in a pill form, GS9620 will be ideal as part of combinations as you suggested.

May I ask why the results of ARC520 have not yet been released and are not expected until end of August?
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Avatar_m_tn
I think because they haven't finished their testing yet on arc520 and it is on schedule and the results will be released (I hope) end of August or early september
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Avatar_m_tn
Or is it possible they are waiting on that conference in Toronto to release the results? I think this is around the same timeframe.
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Avatar_m_tn
Results of ARC-520 have always been due in Q3 and according to the CEO today they are right on schedule. Without giving too much hope it seems to me things are sounding very good as he is preparing for 2b and said everything is going to plan, you would have to imagine he has some indication at this point. First patients were dosed almost 6months ago and thus worked very fast in the chimp
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Avatar_m_tn
Not sure who the author of this is

http://www.investorvillage.com/smbd.asp?mb=2815&mn=2659&pt=msg&mid=14026504

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Avatar_m_tn
Aren't we in Q3 now?
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Avatar_m_tn
Yes, that is why i said they are likely by the end of August. Considering the timeline for the study and data collection, August is a very likely timeframe
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Avatar_m_tn
If all goes to plan when do you think it will be officially available for us?
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Avatar_f_tn
http://www.hepb.org/professionals/hbf_drug_watch.htm
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Avatar_m_tn
There is definitely lots of movement  in drug development for us.

I think they just need to expend the clinical trials to a wider range of possibilities and drug combos.
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