hbvdna will go undetactable but this doesn t mean there is no hbv replication and also has no correlation to hbv infection
hbvdna is only a measure of viral dna in the blood and it is needed just to confirm antiviral is lowering hbv replication, but antiviral has no effect on the infected cells in the liver so the virus will be present in liver cells and also will keep replicating in the liver
the only test to show clearance of hbv infection is hbsag quantitative in iu/ml but antiviral cannot clear hbsag and hbv
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