I hope Mutation test is available in Hitech , Labs Chennai.
HBV - YMDD MUTATION DETECTION -
_http://www.hitechlabsindia.com/2010/testnew.asp?cat=H
how to check the mutation of hbsag ? what is the test name sothat I would check it in india?
Manmadan
hbsag mutants are also at very high risk for cirrhosis and liver cancer so if it was possible to confirm hbsag mutation i d go for treatment immediately
in italy hbsag sequence is available at some hospitals, did you find a place where to have it confirmed?
what about hbvdna and ast/alt
definitely an hbsag mutated case
have you checked vitamin d25oh levels?
interferon would be good but better prepare to have a good interferon response before going at it:
vitamin d levels 80-90ng/ml, to reach these levels you need vit d3 supplemnts 10.000iu daily and need to check calcium and d serum levels every 3 months
if hbvdna is detactable it is better to use tenofovir for 1-3 years to make hbvdna und, rescue your immune response to hbv so that interferon works
see our posts about: aldara, alinia,vitamin d3, simvastatin, all ahev mild effect but all can boost interferon response
do not start interferon ow because hbsag levels over 1500iu/ml have no hbv clerance, sequential treatment with tdf for 1-3 years and then peginterferon add on worked on levles of hbsag around 8000iu/ml but too little patients so it ibetter to lower hbsag as much as possible before interferon and tenofovir, alinia, aldara cream and vit d3 may help a little on this while simvastatin may boost response when interferon is added
Dear Stef,
after almost a year I checked my blood..
hesag -17700 iu/ml
anti hbs - 173 in/lit
Presently not taking any medicines....
can i go for interferon....injecion....
rgds,
Manmadan