i am diagnose in Hepa b as my lab test HBsag- reactive hbe -non reactive hbeag-reactive and my IgM- negative but my IgG- is positive
what does it mean?
only hbsag quant can say how many infected liver we have in the liver, check if you can ship a blood sample somewhere else or the lab can do this
a member of the community said that in ghana all blood samples where sent to south africa for hbvdna pcr and hbsag quant
from what i see in the phillipins there are no good sensibility hbvdna pcr too so you should ask to send the samples to lans wher they can do the tests otherwise it is almost impossible to managea therapy, it is just like giving drugs to all but having to idea if they are really making good or bad.
and what about antioxidant therapy (like heptech products) can make sure you dont develop fibrosis or regress it (of course also diet, weight must be healthy)
is it really effective on hb carriers to eradicate it?
there is nothing to eradicate hbv from a cronic carrier as a general rule but if hbsag quant is low interferon or alinia or combo of interferon+etv or tnf+alinia can eradicate in more than 30% patients
but again it is not possible to mae these therapies without hbsag quant because you will not be able to know if you are responding
here in the philippines that is the only test that they will give us. we cant find hbsag abbot architect. so wat else can we do.. my alt and ast are in normal . do u thnk chronic carriers has the chance to clear this? and what about antioxidant? is it really effective on hb carriers to eradicate it?
check hbcab igm and if available also as hbcab igm quantity in s/co unit so i can tell you the state of immune system and if cronic or acute.after this we can see clearly if hbsag/hbsab is needed or if just hbvdna pcr and alt/ast are enough to monitor
do not make this test anymore:
i was tested hbsag postive last january 2011 my result was 3.491
it is useless for cronic hbv, the number as i told you is not hbsag.that test is only for acute hbv which clears hbsag within a couple of months.if you have it cronic you need to see hbsag quantity and that test doesnt show hbsag quantity
actually that test must be trashed, it is too old and cannot make hbsag quant and cannot detect hbsag mutants, in case of mutants it goes negative but you still have hbsag
if abbott architect or roches quant are not available just check hbsab quant, hbvdna pcr and alt/ast
my sgpt and sgot was 22.0 and my anti Hbs is non reactive.i will have my next test after two months to know if my count is still decreasing.i hope it will became negative soon. im so worried!
you just have to make 2 tests:
hbcab igm and if positive you have had acute hbv which clears 98% times on adults, so you have nothing to worry (the 2% is impaired imune systems or suppressed immune systems)
now you just need to test fo hbsab titer ater 6 months from exposure in case of acute hbv
the hbsag you have done is a very old one and the number is not hbsag quantity, it is the chemical reagent of the test....so just recheck hbsab antibody titer
i suppose yur alt/ast are normal so you dont neeed to rush for these tests