macrophages as the key to hbv/hcv failure of imune response
Macrophages in Hepatitis B and Hepatitis C Virus Infections
Future research is necessary to answer many of the unresolved questions relating to macrophages in HCV and HBV infections, such as the following. Are monocytes and macrophages productively infected by HCV, and is this a significant parameter in immune escape by HCV? Do liver macrophages function efficiently during HCV and/or HBV disease, and can they be a target for immune therapy to control HBV and/or HCV disease?
i believe that the reason of the failed immune response is nagalase which is proven to block macrophages activation.so if nagalase is elevated this is the main reason blocking macrophages (but there maybe others too)
this same thing happens for hiv, cancer and many other cronic diseases so it is very importnat that cronic hbv carriers check their nagalase to know if their immune system works or not
these labs accept blood samples to check nagalase, a test available only at research level out of these 2 labs
http://www.europeanlaboratory.nl/ (this one has a US branch)
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