Aa
A
A
Close
Avatar_universal
new treatment for Chronic hepatitis B
Tenofovir a  nucleotide analogue can now be used for treating CHB,,, can anyone tell me abt the nephrotoxicity profile of the drug
Cancel
3 Answers
Page 1 of 1
Avatar_universal
do you mean that Tenofovir can make HBsAg positive to HBsAg negative? is that for real?
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal
No, it reduces viral load.

I would try googling tenofovir with nephrotoxic.
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Avatar_universal
New Onset or Worsening Renal Impairment

Tenofovir is principally eliminated by the kidney. Renal impairment, including cases of acute renal failure and Fanconi syndrome (renal tubular injury with severe hypophosphatemia), has been reported with the use of VIREAD [See ADVERSE REACTIONS].

It is recommended that creatinine clearance be calculated in all patients prior to initiating therapy and as clinically appropriate during therapy with VIREAD. Routine monitoring of calculated creatinine clearance and serum phosphorus should be performed in patients at risk for renal impairment.

Dosing interval adjustment of VIREAD and close monitoring of renal function are recommended in all patients with creatinine clearance <50 mL/min [See DOSAGE AND ADMINISTRATION]. No safety or efficacy data are available in patients with renal impairment who received VIREAD using these dosing guidelines, so the potential benefit of VIREAD therapy should be assessed against the potential risk of renal toxicity.

VIREAD should be avoided with concurrent or recent use of a nephrotoxic agent.
Comment
Cancel
Avatar_universal
Comment
Comment
Submit Comment
Your Answer
Avatar_universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
new treatment for Chronic hepatitis B
Submit Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Hepatitis B Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1443740527
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top Hepatitis Answerers
Avatar_m_tn
Blank
stef2011
Italy
Avatar_m_tn
Blank
StephenCastlecrag
Australia
Avatar_m_tn
Blank
sorte
Poland
Avatar_f_tn
Blank
Royal36
Avatar_m_tn
Blank
Jatashankar
India
Avatar_f_tn
Blank
flyinsky
paris, France